ID   Y740_AQUAE              Reviewed;         353 AA.
AC   O66948;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Putative transport protein aq_740;
GN   OrderedLocusNames=aq_740;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC06916.1; -; Genomic_DNA.
DR   PIR; A70365; A70365.
DR   RefSeq; NP_213509.1; NC_000918.1.
DR   RefSeq; WP_010880447.1; NC_000918.1.
DR   AlphaFoldDB; O66948; -.
DR   STRING; 224324.aq_740; -.
DR   EnsemblBacteria; AAC06916; AAC06916; aq_740.
DR   KEGG; aae:aq_740; -.
DR   eggNOG; COG0628; Bacteria.
DR   HOGENOM; CLU_041771_2_1_0; -.
DR   InParanoid; O66948; -.
DR   OMA; EIAYVYQ; -.
DR   OrthoDB; 944044at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   PANTHER; PTHR21716; PTHR21716; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..353
FT                   /note="Putative transport protein aq_740"
FT                   /id="PRO_0000148304"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   353 AA;  40159 MW;  CF026520F0833895 CRC64;
     MNKLSLFVYL FFFLSFLFLF LYLLQPFFNP IVWAIVFGIV LYPLYGFIKR KLKSENLAAF
     LVIFIVLVAI VIPFTIFAVI TAQQIIVFSI KVVNFVQTHS VNDLINSLKE IPFLKEKRES
     LEPLLNYLQS EEFRRALINA LNSILTFVGD RLRSYVYTAG TSLFHVFVFL LTLFFILRDG
     EKVLKEIINS IPMKREDLEE ILKTIYRTVL AVIYGTVGTA VAQSIMGFIG YSLAGVEFAL
     IWALITFFAA FVPPFGAAFV WVPMDIYLFT TKGIKEGLIL LFFGTFLIST MDNIVRPLVM
     KQGIKLPYVA LFFSTIGGLI KFGFIGVFLG PIILSTMLAS VKIYRRRVIH SGI