ID   Y740_STRP3              Reviewed;         339 AA.
AC   P0DH04; Q79XB0; Q8K7M5;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=UPF0324 membrane protein SpyM3_0740;
GN   OrderedLocusNames=SpyM3_0740;
OS   Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=198466;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-595 / MGAS315;
RX   PubMed=12122206; DOI=10.1073/pnas.152298499;
RA   Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D.,
RA   Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S.,
RA   Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
RT   "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-
RT   encoded toxins, the high-virulence phenotype, and clone emergence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0324 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE014074; AAM79347.1; -; Genomic_DNA.
DR   RefSeq; WP_011054454.1; NC_004070.1.
DR   AlphaFoldDB; P0DH04; -.
DR   EnsemblBacteria; AAM79347; AAM79347; SpyM3_0740.
DR   KEGG; spg:SpyM3_0740; -.
DR   HOGENOM; CLU_033541_2_1_9; -.
DR   OMA; FGLWCAI; -.
DR   Proteomes; UP000000564; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018383; UPF0324_pro.
DR   PANTHER; PTHR30106; PTHR30106; 1.
DR   Pfam; PF03601; Cons_hypoth698; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..339
FT                   /note="UPF0324 membrane protein SpyM3_0740"
FT                   /id="PRO_0000157465"
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        290..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        314..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   339 AA;  36275 MW;  4C1D2C9A3C94283B CRC64;
     MSTHLRKLPG LLLCLLLALP AWYLGRLFPI IGAPVFAILL GMLLALFYHH RDKTKEGISF
     TSKYILQTAV VLLGFGLNLT QVMAVGMQSL PIIISTIATA LLVAYGLQKW LRLDVNTATL
     VGIGSSICGG SAIAATAPVI KAKDDEVAKA ISVIFLFNML AALLFPSLGQ LLGLSNEGFA
     IFAGTAVNDT SSVTATATAW DALHHSNTLD GATIVKLTRT LAILPITLGL SLYRAKKEHD
     IVTEENFSLR KSFPRFILFF LLASLITTLM TSLGVSADSF HSLKTLSKFF IVMAMAAIGL
     NTNLVKLIKT GGQAILLGSI CWVAITLVSL AMQLSLGIW