ID   Y742_STRPN              Reviewed;         281 AA.
AC   Q97RQ6;
DT   28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=DegV domain-containing protein SP_0742;
GN   OrderedLocusNames=SP_0742;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR   EMBL; AE005672; AAK74881.1; -; Genomic_DNA.
DR   PIR; H95085; H95085.
DR   RefSeq; WP_000219939.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; Q97RQ6; -.
DR   SMR; Q97RQ6; -.
DR   STRING; 170187.SP_0742; -.
DR   EnsemblBacteria; AAK74881; AAK74881; SP_0742.
DR   GeneID; 60232855; -.
DR   GeneID; 66805890; -.
DR   KEGG; spn:SP_0742; -.
DR   eggNOG; COG1307; Bacteria.
DR   OMA; HCENEAD; -.
DR   PhylomeDB; Q97RQ6; -.
DR   BioCyc; SPNE170187:G1FZB-758-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   3: Inferred from homology;
KW   Lipid-binding.
FT   CHAIN           1..281
FT                   /note="DegV domain-containing protein SP_0742"
FT                   /id="PRO_0000209794"
FT   DOMAIN          3..280
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         63
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         91
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
SQ   SEQUENCE   281 AA;  30665 MW;  B016194306843E59 CRC64;
     MTWKIIADSG CDYRQLPTPA INTTFVSVPL TIQVADQVFV DDASLDIDQM METMYATAEA
     SKSACPSPDD YLRAFEGAKN IFLVTITGTL SGSHNSAQLA KNIYLEDHPD TKIHVIDSLS
     AGGEVDLLVE KLNDLIDQGL SFEEVVEAIT AYQEKTKLLF VLAKVDNLVK NGRLSKLIGT
     VVGLLNIRMV GKASETGTLE LLQKARGSKK SVQAAYDELV KAGYAGGRIV MAQRNNEKCC
     QQLSERIRET FPQADIKILP TSGLCSFYAE EGGLLMGYEI D