ID   Y743_MYCGI              Reviewed;         309 AA.
AC   A4T523;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mflv_0743;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mflv_0743;
OS   Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS   PYR-GCK)).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350054;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PYR-GCK;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000656; ABP43228.1; -; Genomic_DNA.
DR   RefSeq; WP_011891649.1; NC_009338.1.
DR   AlphaFoldDB; A4T523; -.
DR   SMR; A4T523; -.
DR   STRING; 350054.Mflv_0743; -.
DR   EnsemblBacteria; ABP43228; ABP43228; Mflv_0743.
DR   KEGG; mgi:Mflv_0743; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; PMDITEL; -.
DR   OrthoDB; 847145at2; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..309
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mflv_0743"
FT                   /id="PRO_0000361158"
FT   BINDING         134
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         163..164
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   309 AA;  33720 MW;  B92334F25BC99C9D CRC64;
     MSSLRTDDDT WDIASSVGAT AVMVAAARAA ETERHDALIN DPYAKVLVEG AGAGAWRFIA
     DEDLVAKASE SDTEVGALFE HMKNYQAVRT HFFDAFFSAA VDAGVRQIVI LASGLDSRAF
     RLPWPAGTVV YEIDQPLVLD YKSSTLAAHG VAPTAERREV PIDLRQDWPA ALVATGFDPA
     RPTAWLAEGL LMYLPADAQD RLFAQITELS APGSQVAAES MGVHAPDRRE RMRERFASIA
     SQIDIEPMDI TELTYEDPDR AEVAEWLAAH GWTAQAVPSQ DAMRRLDRYV EVADSDGQSF
     STFTTGTKL