ID   Y750_TREPA              Reviewed;         223 AA.
AC   O83731;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein TP_0750;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0750;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
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DR   EMBL; AE000520; AAC65716.1; -; Genomic_DNA.
DR   PIR; C71287; C71287.
DR   RefSeq; WP_010882195.1; NC_021490.2.
DR   AlphaFoldDB; O83731; -.
DR   SMR; O83731; -.
DR   STRING; 243276.TPANIC_0750; -.
DR   EnsemblBacteria; AAC65716; AAC65716; TP_0750.
DR   GeneID; 57879273; -.
DR   KEGG; tpa:TP_0750; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_1255493_0_0_12; -.
DR   OMA; HLISIEI; -.
DR   OrthoDB; 1387470at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..223
FT                   /note="Uncharacterized protein TP_0750"
FT                   /id="PRO_0000014256"
FT   DOMAIN          30..204
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   REGION          199..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   223 AA;  25940 MW;  3CE1E08E88FE65BD CRC64;
     MHLKKALCPA LCTFLIHLCL HAGERTVPVD IFLMIDKSRS MQEPGKFSSL HRWVRDEFVS
     SMTIQGDWIT VYQFYEKPEE LITLTLRSEQ DRDKIISVVD SIVPNGRYTD IGRALDTVWE
     IQEKRKDNNR HKVLLLVTDL EHDAPLTSKY RGKQRSFQSP YLVRARRVKH DNWYEITLDM
     AVHDRVAHTA RELYRSIAAA HSKRPTPTPP AKESSPRYTP SLD