ID   Y760_PYRHO              Reviewed;         201 AA.
AC   O58499;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=UPF0056 membrane protein PH0760;
GN   OrderedLocusNames=PH0760; ORFNames=PHCI026;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
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DR   EMBL; BA000001; BAA29851.1; -; Genomic_DNA.
DR   PIR; A71124; A71124.
DR   RefSeq; WP_010884852.1; NC_000961.1.
DR   AlphaFoldDB; O58499; -.
DR   SMR; O58499; -.
DR   EnsemblBacteria; BAA29851; BAA29851; BAA29851.
DR   GeneID; 1443087; -.
DR   KEGG; pho:PH0760; -.
DR   eggNOG; arCOG01997; Archaea.
DR   OMA; LFVIMDP; -.
DR   OrthoDB; 88537at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002771; Multi_antbiot-R_MarC.
DR   PANTHER; PTHR33508; PTHR33508; 1.
DR   Pfam; PF01914; MarC; 1.
DR   TIGRFAMs; TIGR00427; TIGR00427; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..201
FT                   /note="UPF0056 membrane protein PH0760"
FT                   /id="PRO_0000156922"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   201 AA;  21592 MW;  A3C930B2773D2A41 CRC64;
     MLEAIKTFMI LYTGMFAITN PIGAVPVFMS VVGHLPAEIK HEVAKKVSIT VFITLTVFAL
     VGQWIFKFFG SSIDAFAIAG GILLFRMGME MLSGKLSSVK IDEEDVTLEE VAVIPLAIPL
     ISGPGAITTV MLYMTKESPG IVILTIIAIG LTTYGILYSG NKIIERLGRV GVKVTTRMMG
     LILTSMAMQM IINGIKGAFG I