ID   Y7728_DICDI             Reviewed;        1204 AA.
AC   Q54JK1;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=TPR repeat-containing protein DDB_G0287999;
GN   ORFNames=DDB_G0287999;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000107; EAL63425.1; -; Genomic_DNA.
DR   RefSeq; XP_636930.1; XM_631838.1.
DR   AlphaFoldDB; Q54JK1; -.
DR   STRING; 44689.DDB0187728; -.
DR   PaxDb; Q54JK1; -.
DR   EnsemblProtists; EAL63425; EAL63425; DDB_G0287999.
DR   GeneID; 8626405; -.
DR   KEGG; ddi:DDB_G0287999; -.
DR   dictyBase; DDB_G0287999; -.
DR   HOGENOM; CLU_270461_0_0_1; -.
DR   InParanoid; Q54JK1; -.
DR   PRO; PR:Q54JK1; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   InterPro; IPR045208; IF4G.
DR   PANTHER; PTHR23253; PTHR23253; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..1204
FT                   /note="TPR repeat-containing protein DDB_G0287999"
FT                   /id="PRO_0000347001"
FT   REPEAT          263..296
FT                   /note="TPR 1"
FT   REPEAT          379..412
FT                   /note="TPR 2"
FT   REPEAT          583..617
FT                   /note="TPR 3"
FT   REGION          32..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          360..387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          639..660
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          761..797
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        765..782
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1204 AA;  141007 MW;  8A70AABE84924CAE CRC64;
     MITLRKSLSK SCKDLRILNG TTYVKGFCST TTTDTTTTTS TSTTTDTDTN SEKSNKEKLF
     HQINELTKQS SFNKVLFYKK SAHETEGYSY KERQQFKQKQ QKIKQIKHNQ QLKQKQQIEQ
     QKQKKLEQQQ QQQQLELEKK QKFEQQLEQQ QREQNQISLL EKSKDLESIN DFGDFDFREL
     ETKPLFSVPN VLINYLENEK TLSDHQKSDV VGSFYSDGEI PSVPHINLEE YTRSVLIEAY
     LEVCKPEYAF YYFKQSENNK TNSKGLLLMI EFYIKIGDID SAFKFFEVNF KDYKDLISTN
     DYYKLFNGLI TYSIDNQENI FDIKNKFFNV IINDNINNDI EKFNVGSLAS MIESITPKYQ
     PPPQEQQLMD DDSNSNSNND SNNIIKNSSS KLEFNDDCVS NYKKLVNFDQ LYSIYKNNYK
     KYTSDQRLII LSCILKYSII TADIELFLNT VNRVLVKDGI EKVEIPILQI LFEAYTHTIP
     SDKPELVGQL KYLLTNYIKD MDSSDNGYKS ISKLIAYNFS FKGDIKNSIY DQLCGIGIKS
     IEIDIENNIE NSVLINKLKQ EQREKERNQF IIFIQSIFPE DRIQHFVETA LIYLINDNSY
     QEAVKLYIYF LKEGSVTGID IFLKYHELSY KNIVYNNNNN NNNNNNNNNN NNNNNNNNNN
     IKNFTTFSEN DHKTLKTFWE RIKNNYVNNN NKQQQQEERD IENEFIFIGK GEINNDQLLE
     KFQYIKEFRN IKSFFNSYEE NLNPNDFINY IKNIINKVND DDNDNDNNNN NNNNNNNNND
     DDDGGGHGGG DVFKTTTPKK VKPLISTIQK SQNELPTTTT YKEIIENTSF FRNQQYNFNR
     ELSSTLNSPK SRLDLERLQS FLNCKSHTES MSFQQLCICL ELVGDTGFKY DFYKNLNHIQ
     KTLIITPQLC KNLFSTVTMD ESIDILRRGL SRISPENLKS LGIWDGVFQG LLKDPLKTPL
     ANFLMYNGFI SKSSFDRYSY CQQIINTDID AYYFFLDPSI SYYDTFGGDI EDASNYNLKK
     DSSKTFFKPM EDFFITYLDT FFKASSPHEI SQRPDYQTQF SNYTILSLIR LGKLNEAFKE
     IESLSPAKYN ATTIGLVVFI YSKRYKQDKS KFLVEIQSLI QRIIFDLENK MGSEDARSYF
     HKYILKSLII NYGNIEMDNL IANVDVPKVL KDIDNSLAPN FDRRLIRKLF KVRGYIKYRF
     YRLN