ID   Y7758_DICDI             Reviewed;         878 AA.
AC   Q55G98;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=von Willebrand factor A domain-containing protein DDB_G0267758;
GN   ORFNames=DDB_G0267758;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000003; EAL73332.1; -; Genomic_DNA.
DR   RefSeq; XP_647286.1; XM_642194.1.
DR   AlphaFoldDB; Q55G98; -.
DR   SMR; Q55G98; -.
DR   PaxDb; Q55G98; -.
DR   EnsemblProtists; EAL73332; EAL73332; DDB_G0267758.
DR   GeneID; 8616092; -.
DR   KEGG; ddi:DDB_G0267758; -.
DR   dictyBase; DDB_G0267758; -.
DR   eggNOG; ENOG502QRPK; Eukaryota.
DR   HOGENOM; CLU_327738_0_0_1; -.
DR   InParanoid; Q55G98; -.
DR   OMA; NHKESQI; -.
DR   PhylomeDB; Q55G98; -.
DR   PRO; PR:Q55G98; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..878
FT                   /note="von Willebrand factor A domain-containing protein
FT                   DDB_G0267758"
FT                   /id="PRO_0000389211"
FT   DOMAIN          36..169
FT                   /note="VIT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00801"
FT   DOMAIN          316..496
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   REGION          595..638
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          752..774
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        752..769
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   878 AA;  99446 MW;  1CA07E82B645921B CRC64;
     MSSDNNDNNN NHSYKEANYY NYYRLLENNL KKKSRGLFLT ENNKKKSKVF KLTKFSIDTE
     INDCSSTSKW TQIYSNDSKT PIEARYKIPL HPTWIITDFR VESQDKVVVL IGKIKEHEKA
     LNNYNDTIAN GGQSFLASKS SIEDLDFFNL NIGNLPPNET VKITLTITSE IGTHINGQLH
     YYLHHSLFPT YNFNFNLNII IKLSNSIESI INWYGNSKRI LNINSSNTGC GSDDGDDDVI
     KVLYNNSNNK EIKIKSNDKL NSIEDSLVLI IQPSIINDEP KSMIEYNKIE NSLAVSINYY
     SSFKDIKIED MNQKSEFIFL IDCSGSMVGE PMRKVKRAME IIIRSLNENQ HRVNVVCFGS
     SFKKVFKVSR DYNDETLECL SKYIQSIEAN LGGTELLTPI KNILSSPPNP EYPRQLFILT
     DGEAPHRDKI IHYLSKESNT TRIFTYGIGD SVDIDLIIGL SNACKGHYEF ITDNDNFEKQ
     VMKLLNISLK PMFSNIKLDL STLFSNNKNK NKNNNNCKED IIIQSPSQIR PLFYQERMIV
     YLMIESLSTR LKDIINDSIE NSKPLIITMT CDGPKGDKLS IPIELDLKNN CIISSSSSSS
     SSSSSSSSSS SSSSSSSSSS SSSTTTATTN QNQIHRLSAY HQIKDLEEKE RKKKKDNKTR
     IVELSKKYGI LSKHTSFIVK CESTKPTLES MDFIDIIDQF SFENQVSATK NKSQCLLTKS
     KKSKTAAPTT TTTTTITKKR FSDVDEDISR QSVKKSKKSE TKEETTKTTS SKTKSSSSFD
     LIDLLRIQRA NGSWTKSTIS QMGISIGNAP VELSSDQLYN IWVTLIVISK IIKLFPNEKI
     EYEFAIQKSK KWVKLELSKL NLPNTTFDKF SLKANSLC