ID   Y775_HAEIN              Reviewed;         315 AA.
AC   P44876;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator HI_0775;
GN   OrderedLocusNames=HI_0775;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC22434.1; -; Genomic_DNA.
DR   PIR; C64092; C64092.
DR   RefSeq; NP_438934.2; NC_000907.1.
DR   AlphaFoldDB; P44876; -.
DR   SMR; P44876; -.
DR   STRING; 71421.HI_0775; -.
DR   DNASU; 950670; -.
DR   EnsemblBacteria; AAC22434; AAC22434; HI_0775.
DR   KEGG; hin:HI_0775; -.
DR   PATRIC; fig|71421.8.peg.814; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_2_6; -.
DR   OMA; LPAPYCR; -.
DR   PhylomeDB; P44876; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..315
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   HI_0775"
FT                   /id="PRO_0000105810"
FT   DOMAIN          16..74
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        34..53
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   315 AA;  36679 MW;  C38F209C599BDB9C CRC64;
     MLYFVKMAVL RGVKMMDIRH LRYFVSIVDN DFNLSRASQN LYVSQPALSM MITEFENREN
     IQIFKRASGK IIGLTFAGEN YYRDAKEVIK RYNDMRTNLY KSKDCKKGTI TIGIPPLVLS
     AVFSSVLPHL ILKNPDINFI IKEIGAYALK SELLLDKVDL AVLLYPERIS KNIIDSIEIH
     SSELALFLSP KHVLAKKQQI TWADLHQQKM AIFDQTFMIH HHLKEAFERN NCYPDIVLDS
     SCWDFLLSAV KTNKELLTIL PLPMAELYHS KEFLCRKIES PVPWKVTLCR QRKTVYTHLE
     EYIFDKLLEA FRPTK