ID   Y7786_DICDI             Reviewed;         528 AA.
AC   Q55G75;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=PH domain-containing protein DDB_G0267786;
GN   ORFNames=DDB_G0267786;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=12963116; DOI=10.1016/s0925-4773(03)00136-9;
RA   Muramoto T., Suzuki K., Shimizu H., Kohara Y., Kohriki E., Obara S.,
RA   Tanaka Y., Urushihara H.;
RT   "Construction of a gamete-enriched gene pool and RNAi-mediated functional
RT   analysis in Dictyostelium discoideum.";
RL   Mech. Dev. 120:965-975(2003).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=18559084; DOI=10.1186/1471-2164-9-291;
RA   Sillo A., Bloomfield G., Balest A., Balbo A., Pergolizzi B., Peracino B.,
RA   Skelton J., Ivens A., Bozzaro S.;
RT   "Genome-wide transcriptional changes induced by phagocytosis or growth on
RT   bacteria in Dictyostelium.";
RL   BMC Genomics 9:291-291(2008).
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DR   EMBL; AAFI02000003; EAL73346.1; -; Genomic_DNA.
DR   RefSeq; XP_647308.1; XM_642216.1.
DR   AlphaFoldDB; Q55G75; -.
DR   SMR; Q55G75; -.
DR   PaxDb; Q55G75; -.
DR   PRIDE; Q55G75; -.
DR   EnsemblProtists; EAL73346; EAL73346; DDB_G0267786.
DR   GeneID; 8616119; -.
DR   KEGG; ddi:DDB_G0267786; -.
DR   dictyBase; DDB_G0267786; -.
DR   eggNOG; ENOG502RENY; Eukaryota.
DR   HOGENOM; CLU_516246_0_0_1; -.
DR   InParanoid; Q55G75; -.
DR   OMA; TPIDWGE; -.
DR   PhylomeDB; Q55G75; -.
DR   PRO; PR:Q55G75; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR026088; Niban-like.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR14392; PTHR14392; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..528
FT                   /note="PH domain-containing protein DDB_G0267786"
FT                   /id="PRO_0000368214"
FT   DOMAIN          59..180
FT                   /note="PH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
SQ   SEQUENCE   528 AA;  60869 MW;  48FE039F7527873A CRC64;
     MDAQIKNEIV ELTKAMLETF TKEYIKAYTI QITKKAIKDA KAIPSPYLLE PRPRDHDKSD
     VFSGYLVKLG AIRKNWLKRH FVVRYDYSID YFVDDKHTNK KGTINLCGYS VNDDPNKSGL
     DRILKIAEKM GVDTSSIPKP AQLPPFTIEL YHYSRRCYYI QCANEEEFKE WIEIFKTCCR
     RSHGFKNKDP CHIAAFGIAV RNTRWSLGRW GWFGYGGNEN QILSDIILDE IEYDILGRAL
     SKLPNAPWFI RNYLRNKMMT VIEGMVSSAV APAWTGLSKT VEELRPTIEP RIKNQVDPIA
     QAQTNIINKM RESMMSQIKP AMEEHVNKHL KKIIGEIRTP IENGFDESLK IWNEKTNAYN
     GNGSTESFSS YRSYPNSYWT MYPAKDKISP LYSIVEEYRP IFRDYSSYFI CYDIKESINN
     MAYDGAYTLE KTVTQDQVDV ASAKNQTHSK YQHDVILGTN MQLKFVVREM VKPTLCKIIN
     PLTKPLLNTL SSSIPSAIGD FIDINELYNQ LVDDILNDST QVVIDELN