ID   Y778_AERPE              Reviewed;         329 AA.
AC   Q9YDZ1;
DT   25-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein APE_0778 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=APE_0778;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
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DR   EMBL; BA000002; BAA79756.1; -; Genomic_DNA.
DR   PIR; D72669; D72669.
DR   AlphaFoldDB; Q9YDZ1; -.
DR   SMR; Q9YDZ1; -.
DR   STRING; 272557.APE_0778; -.
DR   EnsemblBacteria; BAA79756; BAA79756; APE_0778.
DR   KEGG; ape:APE_0778; -.
DR   eggNOG; arCOG04152; Archaea.
DR   OMA; MWETIRT; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..329
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   APE_0778"
FT                   /id="PRO_0000144852"
FT   DOMAIN          142..200
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        153..172
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   329 AA;  37235 MW;  DA5589FDE011AD79 CRC64;
     MVQGLPGEFE DYLYRVIASL YRYAERLVVV DYPSSPTRRS IDLIVSLPGS RVVLIKAIYD
     ASLISKKEVE ELSAVANSLG VSAVIIAERM GREDLLTGVV YDRYGVNMVN LETFENFVSG
     REEVYVTRYK DIYTVSISSE KLREKRLEKG LSLGHLAYML KTSRKSIYEY ERGVMSPSVE
     KAEKLVDILG EEILEPIDIL TSPRKPVSKR DFDKPEEALV GEKLLELGFK VSHAKRTVVD
     LVAGRSGEEG VGSRIMIVVK RSREGRERMM SRIMKGVKMG SILSSSLYAV VNREEKSLIK
     DIDYTKTIVK DVREFINDVS RGRVEENEE