Y781_METJA
ID Y781_METJA Reviewed; 721 AA.
AC Q58191;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Uncharacterized protein MJ0781;
DE Contains:
DE RecName: Full=Mja klbA intein;
GN OrderedLocusNames=MJ0781;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- PTM: This protein undergoes a protein self splicing that involves a
CC post-translational excision of the intervening region (intein) followed
CC by peptide ligation. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GSP E family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; L77117; AAB98770.1; -; Genomic_DNA.
DR PIR; E64397; E64397.
DR PDB; 2JMZ; NMR; -; A=398-577.
DR PDB; 2JNQ; NMR; -; A=398-577.
DR PDBsum; 2JMZ; -.
DR PDBsum; 2JNQ; -.
DR AlphaFoldDB; Q58191; -.
DR BMRB; Q58191; -.
DR SMR; Q58191; -.
DR STRING; 243232.MJ_0781; -.
DR EnsemblBacteria; AAB98770; AAB98770; MJ_0781.
DR KEGG; mja:MJ_0781; -.
DR eggNOG; arCOG01819; Archaea.
DR HOGENOM; CLU_005379_0_1_2; -.
DR InParanoid; Q58191; -.
DR OMA; TGHDGCS; -.
DR PhylomeDB; Q58191; -.
DR EvolutionaryTrace; Q58191; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001482; T2SS/T4SS.
DR Pfam; PF00437; T2SSE; 1.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; SSF51294; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR01443; intein_Cterm; 1.
DR TIGRFAMs; TIGR01445; intein_Nterm; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP-binding; Autocatalytic cleavage; Membrane;
KW Nucleotide-binding; Protein splicing; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..404
FT /note="Uncharacterized protein MJ0781, 1st part"
FT /evidence="ECO:0000255"
FT /id="PRO_0000013122"
FT CHAIN 405..572
FT /note="Mja klbA intein"
FT /evidence="ECO:0000255"
FT /id="PRO_0000013123"
FT CHAIN 573..721
FT /note="Uncharacterized protein MJ0781, 2nd part"
FT /evidence="ECO:0000255"
FT /id="PRO_0000013124"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 308..315
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT HELIX 422..432
FT /evidence="ECO:0007829|PDB:2JMZ"
FT TURN 434..436
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 446..448
FT /evidence="ECO:0007829|PDB:2JMZ"
FT TURN 450..452
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 455..457
FT /evidence="ECO:0007829|PDB:2JMZ"
FT TURN 461..464
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 468..470
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 473..477
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 481..484
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 501..506
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 509..514
FT /evidence="ECO:0007829|PDB:2JMZ"
FT HELIX 515..517
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 522..527
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 529..536
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 542..545
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 549..553
FT /evidence="ECO:0007829|PDB:2JMZ"
FT TURN 555..557
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 558..564
FT /evidence="ECO:0007829|PDB:2JMZ"
FT STRAND 568..571
FT /evidence="ECO:0007829|PDB:2JMZ"
SQ SEQUENCE 721 AA; 82743 MW; 13B76CEC7976F0F3 CRC64;
MIIKNQLIFV NFYVILIIWW FVMGILDKIQ KKSEKIEKEK KSETVIPSDT KLKPIEPHPT
INKKATVGND ETILDTYSIK IDEIEMEVVI KREEGYIYYL VPEIDKINMS LSKLTKDHLN
HIKSQISDLG LIEYDQIREY LTNFSMRYNL AIPYIDSLAK FFYLVIGRLG LLEVPLNDDR
LEEVMVNGYN VPVFVFHRKH QMCETNIVLD RNEVDRIIES IANLVNRPID SRVPMLDAFL
PDGSRVNATT ADITMNGATL TIRKFSKNPL TVIDLINFGT LDIDTAAFLW QAVEGYFGAK
PANTLIAGGT GSGKTTLLNV LSLFSMYNER IITIEDTPEL QIPHKHVIKM VTRPARPGMP
EYEVTMDDLI KNALRMRPDR IFVGEVRGKE AHSLLVAMNT GHDGALAYDE PIYLSDGNII
NIGEFVDKFF KKYKNSIKKE DNGFGWIDIG NENIYIKSFN KLSLIIEDKR ILRVWRKKYS
GKLIKITTKN RREITLTHDH PVYISKTGEV LEINAEMVKV GDYIYIPKNN TINLDEVIKV
ETVDYNGHIY DLTVEDNHTY IAGKNEGFAV SNCSGTLHAN SADEAILRLT SPPMNVPKIM
LTALNFIINQ QRIRRAGKTI RRILGIVEIV KGGGEGHEFA KTTLYEYNGL KDSLERRGIC
MWEEEVCEIA GITKEELLRD RENRKKVLSY LYKNNIRKLE NVSDYIMRYQ VDPEKLLRSI
R
