ID   Y788_ARCFU              Reviewed;         308 AA.
AC   O29470;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Uncharacterized transporter AF_0788;
GN   OrderedLocusNames=AF_0788;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB90451.1; -; Genomic_DNA.
DR   PIR; D69348; D69348.
DR   AlphaFoldDB; O29470; -.
DR   SMR; O29470; -.
DR   STRING; 224325.AF_0788; -.
DR   PRIDE; O29470; -.
DR   EnsemblBacteria; AAB90451; AAB90451; AF_0788.
DR   KEGG; afu:AF_0788; -.
DR   eggNOG; arCOG00271; Archaea.
DR   HOGENOM; CLU_033863_21_3_2; -.
DR   OMA; TFLAVQY; -.
DR   PhylomeDB; O29470; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000620; EamA_dom.
DR   Pfam; PF00892; EamA; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..308
FT                   /note="Uncharacterized transporter AF_0788"
FT                   /id="PRO_0000108203"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          52..166
FT                   /note="EamA 1"
FT   DOMAIN          178..306
FT                   /note="EamA 2"
SQ   SEQUENCE   308 AA;  34282 MW;  BCD0ED6AEA920D88 CRC64;
     MGEDRRSLRV DYDDNFLRNN ICSLKVSFIK QQGGAEGVKR LYADLGLALV ALIWGSTFPV
     VKIALDSMSP FAFNTVRFFI ACLFFLPFLK GWDFKDGFKI GIASFLGYTF QTVGLDYTTA
     TNAGFITSTY VVLAPIISWL VYKDVFDKRD VSGVLLAFVG FYFLSGYSGF NIGDILMLFC
     ALFFGAEIAM ISHYSRLSNP TMLAFWQSFA IFILSAPFAV FTTTKFEINT TVILCLLITA
     FFATFVAKML QNWLQSYTKS SDAAVILSLE GVFAHLFSVA VLAEILTPVQ YFGAFLILLA
     VIIVSLRV