Y7897_DICDI
ID Y7897_DICDI Reviewed; 1415 AA.
AC Q54XG9;
DT 20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=G8 domain-containing protein DDB_G0278975;
DE Flags: Precursor;
GN ORFNames=DDB_G0278975;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the comF family. {ECO:0000305}.
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DR EMBL; AAFI02000026; EAL67909.1; -; Genomic_DNA.
DR RefSeq; XP_641881.1; XM_636789.1.
DR AlphaFoldDB; Q54XG9; -.
DR STRING; 44689.DDB0304438; -.
DR PaxDb; Q54XG9; -.
DR EnsemblProtists; EAL67909; EAL67909; DDB_G0278975.
DR GeneID; 8621807; -.
DR KEGG; ddi:DDB_G0278975; -.
DR dictyBase; DDB_G0278975; -.
DR eggNOG; ENOG502RSSR; Eukaryota.
DR HOGENOM; CLU_005143_0_0_1; -.
DR InParanoid; Q54XG9; -.
DR OMA; ISMTHGD; -.
DR PhylomeDB; Q54XG9; -.
DR PRO; PR:Q54XG9; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019316; G8_domain.
DR Pfam; PF10162; G8; 1.
DR SMART; SM01225; G8; 1.
DR PROSITE; PS51484; G8; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..1415
FT /note="G8 domain-containing protein DDB_G0278975"
FT /id="PRO_0000393594"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 566..692
FT /note="G8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00817"
FT REPEAT 819..841
FT /note="PbH1 1"
FT REPEAT 842..864
FT /note="PbH1 2"
FT CARBOHYD 245
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 366
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 428
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 466
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 579
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 844
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 985
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1009
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1023
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1099
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1244
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1342
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1415 AA; 156799 MW; EB6CBF80C16B166B CRC64;
MKINKIILFF FLSCLYLFSS SVSAQQLLGE IEITEKSFTI DASVINTKIN YLIDNTITKP
KLSVTSIFGE ATSIDDILRI SDDKKSLTFG DYTSSTLSSS NKLVSKINLN SLILISFSTI
ITFGLFTKNN PRSSSKPLLF IVLLICISIF NLSNSIKISE VSVRIDIKVP STFKFDSLIL
TLGSGSSIIN GLIASSLKID GCTTNSKDHS IELNQISISS ELNICSTKEI NINEIQLTST
NVKLNLTSSS NVNLDFHNGY SGSFSINTND LTLDSACETF KDSNTGIIIG TCNGGSDNSK
LSITAITGKT VVSNAEITCP IDNSWRVTVG ADNVPPSPSI ITSQPATDFI FKKNDLVYMA
QYGYSNQSIT DGPVENSFIV SYPAYIPPSN FLVSKIIGSP TFKANVKYQF SISVKLGQPL
GSFNRIQNMS LYFFNPRDIT DPINGASQYY ELKDTIPLFV HTFEGNFTSN TEFALTKIEF
TPTVDIGTSI FGLRIFRTGF TGGDVVTVII KDMKFTILPK TITQPTLLIK DSELVNLPKP
STSFDPQDSS TCPYLANDLV HWHNPSTWPN GIIPSPSSNI TLPEGKKVLI SPCSISQTQV
YKWIKVPSTS ELIFADSPMD FHVKDIYVEG KFIMGTTKCR YNSKINIIFH GEKTLSDTIS
QYYGSKGIGV SSSGFISVHA KQYHNTWSKL SASAWSGDYV VYIQDNVNWE VGQKVVVITS
YYQDEDNNQN EVMTIAAIQG KTIQFTEPLK FFHYGGQEYQ AEIALLTRRI TFQSSDVNQF
GGHVMVMGEG QFAGLGLIGM GQRNIKARYP LHYHLGKVLK NSYISDCSVT NSYYRCYTIH
GTNNVTLTRN VAFDVSGHCY YLEDGVEMDN TISFNLAAYV HPIGRPAAGP SQIGEVFVES
DNLRQPADCA ASGYYITNAW NKIIGNTASG GWAGYAFPNL DKPIGNHRTV QMIPKAYSTK
VFEGNTGHSS GHFFITGATI YVGANLTYNE VDGLLYYDSG RFERFTYKNG TVVYGNEVPM
RFNNTKIYLS NFGIGHWGEY VEVVSYESHD NIRSASIFGE AWLSKAIVNG NSNNIARSIN
FNKQGFQYYD TYVKTVLSNI SFRNYIRNPK SLNDEDDNRA IISMTHGDVF KPQGISTARA
ISFVNVAKSQ IVGHQVLPTS GSRYFNFIDW DSSITGKKPG QPALVGSHEL WYKFDNTCEY
NSDWTCHICE KGNKEIANIQ FIIPGLIDDG VLVYDSFENL NVGNISLFGS GITERRSTIV
TKNQGVTGVS NMGWYLYLKA GSPKYMKIWL SQVVYGQHIF LALPYPTQTT FIIKSNYIWG
SAINYNHVFS LASSAADVRS GNGTKYYFDG NFLYVKLVNL VLTGDPSEYY ERDGVKVYWV
RNSFSVSIEA TNTVTPPTSD GFFKNLPDNL PSSSL
