ID   Y792_METTH              Reviewed;         346 AA.
AC   O26883;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-2002, sequence version 2.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=UPF0219 protein MTH_792 {ECO:0000255|HAMAP-Rule:MF_01409};
GN   OrderedLocusNames=MTH_792;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. UPF0219 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01409}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB85292.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000666; AAB85292.1; ALT_INIT; Genomic_DNA.
DR   PIR; F69205; F69205.
DR   RefSeq; WP_048060900.1; NC_000916.1.
DR   AlphaFoldDB; O26883; -.
DR   SMR; O26883; -.
DR   IntAct; O26883; 1.
DR   STRING; 187420.MTH_792; -.
DR   EnsemblBacteria; AAB85292; AAB85292; MTH_792.
DR   GeneID; 1471200; -.
DR   KEGG; mth:MTH_792; -.
DR   PATRIC; fig|187420.15.peg.777; -.
DR   HOGENOM; CLU_039592_7_0_2; -.
DR   OMA; YAKHKGK; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 1.
DR   HAMAP; MF_01409; UPF0219; 1.
DR   InterPro; IPR013747; ACP_syn_III_C.
DR   InterPro; IPR004656; FabH-rel.
DR   InterPro; IPR013528; HMG_CoA_synth_N.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF08541; ACP_syn_III_C; 1.
DR   Pfam; PF01154; HMG_CoA_synt_N; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR00748; HMG_CoA_syn_Arc; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..346
FT                   /note="UPF0219 protein MTH_792"
FT                   /id="PRO_0000057618"
SQ   SEQUENCE   346 AA;  36718 MW;  E0452F31559552C8 CRC64;
     MAGIVGYGVY IPSYRIKVEE IARVWGDDPQ AISRGLVVEE KSVPGPDEDT ATISVEAARN
     ALRRSQIDPS EIGAVYVGSE SHPYAVKPTA TIVAEAVEAT PEMTAADLEF ACKAGTAGIQ
     ACMGLVDSGI IKYGLAVGAD TAQGAPGDAL EYTASAGGAA YVIGGKNCLA DIKETYSFTT
     DTPDFYRREG MPYPRHGGRF TGEPAYFKHV LGAARGMMEK TGLSADDFDY AVFHQPNGKF
     YLKAARKLGF ESEQVKPGLL TPVIGNTYSG ATPVGLAATL DVAEPGARIL AVSYGSGAGS
     DAFIIEVNDL IEERRDLAPS VAEIIKNKRY VDYALYAKFK GKLRMA