Y7958_DICDI
ID Y7958_DICDI Reviewed; 729 AA.
AC Q55FT8;
DT 03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Bromo and FHA domain-containing protein DDB_G0267958;
GN ORFNames=DDB_G0267958;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000003; EAL73432.1; -; Genomic_DNA.
DR RefSeq; XP_647445.1; XM_642353.1.
DR AlphaFoldDB; Q55FT8; -.
DR SMR; Q55FT8; -.
DR STRING; 44689.DDB0220692; -.
DR PaxDb; Q55FT8; -.
DR PRIDE; Q55FT8; -.
DR EnsemblProtists; EAL73432; EAL73432; DDB_G0267958.
DR GeneID; 8616252; -.
DR KEGG; ddi:DDB_G0267958; -.
DR dictyBase; DDB_G0267958; -.
DR eggNOG; ENOG502RC8T; Eukaryota.
DR HOGENOM; CLU_380118_0_0_1; -.
DR InParanoid; Q55FT8; -.
DR OMA; ANDNDFM; -.
DR PRO; PR:Q55FT8; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0033186; C:CAF-1 complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 1.20.920.10; -; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; SSF47370; 1.
DR SUPFAM; SSF49879; SSF49879; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain; Coiled coil; Reference proteome.
FT CHAIN 1..729
FT /note="Bromo and FHA domain-containing protein
FT DDB_G0267958"
FT /id="PRO_0000388242"
FT DOMAIN 112..167
FT /note="FHA"
FT DOMAIN 525..600
FT /note="Bromo"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00035"
FT REGION 46..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 315..352
FT /evidence="ECO:0000255"
FT COILED 659..718
FT /evidence="ECO:0000255"
FT COMPBIAS 46..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..341
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..729
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 729 AA; 81963 MW; 3B52B6AC3F9BF057 CRC64;
MADSVTIGQL EKLSVQCDKE NQHVENKENN INSDNINLLE ATKTTLPIPN TSNTNPPMNQ
SSSPTTTTTT PTTTTTPTTA EPAKKRKIFA KLHLLNRDGS VKNYFEMKKT KLIIGSDTEL
ADIQVVRPGI YPKHVEIIYD KEKKKFYLNP LIDPKDSDNV RLNFVPFLHK KEVLGNGDII
SIGFRSIKME FIEKVTVDQL VQPEKQYIPS NTPTCITNTP IQTPPTTSPP SSTTTNKKDN
TSTNVTKKPI ATVPSTTTST KKSSVVPESK PATKTITKET PKPTKTTTTT TVTTSKPTVK
PTAVKKSIND DDYGDDYNEE EDDDDEEEEE EEEEEEEEEE VESKQIKVVN SKPNDDDMSC
KKPMKYTNTN EEMRKSLASN VGGINSKIIS KGDSVRNLLP ISSRRPTAPV TPTKPTSTKK
VTTPKKATVV KPPKESKVPK VPKVPKVPKA AVVASIDENG KEDYIRLISF KKAKDIVKAF
QSHEKLVKSK NNGHGNISNE KKEILKCFEV LDQINWRLST DKPGDSRPIS SYFKNIPSLS
EFDSELLTDY YSMISEPMSI NSILSSVIYT ADYNIDNCLD DFNQVLENSM TYNSENSIIY
WLAHYCKIEL YKALSNSGII QNKLYLDIKK DSETFLKSIG TQLKGDGISL PQIIAQSVSK
NKEQTVPQEE DEEEEEEEEE EEEEEEEGEE GKEDEEEEEK EEEEGEENEE EEDVEIDDCE
IDQESDDDQ
