ID   CASP_PONAB              Reviewed;         678 AA.
AC   Q5R8V1;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Protein CASP;
GN   Name=CUTL1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in intra-Golgi retrograde transport.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer; disulfide-linked. Interacts with GOLGA5 (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC       pass type IV membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CASP family. {ECO:0000305}.
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DR   EMBL; CR859648; CAH91809.1; -; mRNA.
DR   RefSeq; NP_001128945.1; NM_001135473.1.
DR   AlphaFoldDB; Q5R8V1; -.
DR   SMR; Q5R8V1; -.
DR   STRING; 9601.ENSPPYP00000019564; -.
DR   PRIDE; Q5R8V1; -.
DR   GeneID; 100171552; -.
DR   CTD; 1523; -.
DR   eggNOG; KOG0963; Eukaryota.
DR   InParanoid; Q5R8V1; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR012955; CASP_C.
DR   Pfam; PF08172; CASP_C; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Disulfide bond; Golgi apparatus; Membrane; Phosphoprotein;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..678
FT                   /note="Protein CASP"
FT                   /id="PRO_0000071792"
FT   TOPO_DOM        1..619
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        620..640
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        641..678
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   COILED          67..450
FT                   /evidence="ECO:0000255"
FT   COILED          502..556
FT                   /evidence="ECO:0000255"
FT   MOD_RES         586
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q13948"
SQ   SEQUENCE   678 AA;  77489 MW;  A8EB534BFEE97282 CRC64;
     MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR EFKKNTPEDL
     RKQVAPLLKS FQGEIDALSK RSKEAEAAFL NVYKRLIDVP DPVPALDLGQ QLQLKVQRLH
     DIETENQKLR ETLEEYNKEF AEVKNQEVTI KALKEKIREY EQTLKNQAET IALEKEQKLQ
     NDFAEKERKL QETQMSTTSK LEEAEHKVQS LQTALEKTRT ELFDLKTKYD EETTAKADEI
     EMIMTDLERA NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE
     VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLSAKNSTLK QLEEKLKGQA
     DYEEVKKELN ILKSMEFAPS EGAGTQDAAK PLEVLLLEKN RSLQSENAAL RISNSDLSGR
     CAELQVRVTE AVATATEQRE LIARLEQDLS IIQSIQRPDA EGAAEHRLEK IPEPIKEATA
     LFYGPTAPAS GALPEGQVDS LLSIISSQRE RFRARNQELE AENRLAQHTL QALQSELDSL
     RADNIKLFEK IKFLQSYPGR GSGSDDTELR YSSQYEERLD PFSSFSKRER QRKYLSMSPW
     DKATLSMGRL VLSNKMARTI GFFYTLFLHC LVFLVLYKLA WSESMERDCA TFCAKKFADH
     LHKFHENDNG AAAGDLWQ