ID   Y808_METJA              Reviewed;         333 AA.
AC   Q58218;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Uncharacterized protein MJ0808;
GN   OrderedLocusNames=MJ0808;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000305};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine. {ECO:0000305};
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DR   EMBL; L77117; AAB98808.1; -; Genomic_DNA.
DR   PIR; H64400; H64400.
DR   RefSeq; WP_010870318.1; NC_000909.1.
DR   AlphaFoldDB; Q58218; -.
DR   SMR; Q58218; -.
DR   STRING; 243232.MJ_0808; -.
DR   PRIDE; Q58218; -.
DR   DNASU; 1451690; -.
DR   EnsemblBacteria; AAB98808; AAB98808; MJ_0808.
DR   GeneID; 1451690; -.
DR   KEGG; mja:MJ_0808; -.
DR   eggNOG; arCOG00946; Archaea.
DR   HOGENOM; CLU_044176_1_0_2; -.
DR   InParanoid; Q58218; -.
DR   OMA; YHFYPGS; -.
DR   OrthoDB; 39920at2157; -.
DR   PhylomeDB; Q58218; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR027596; AmmeMemoSam_rS.
DR   InterPro; IPR034457; Organic_radical-activating.
DR   InterPro; IPR016431; Pyrv-formate_lyase-activ_prd.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR30352; PTHR30352; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   PIRSF; PIRSF004869; PflX_prd; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01101; Uncharacterised_Radical_SAM_Su; 1.
DR   TIGRFAMs; TIGR04337; AmmeMemoSam_rS; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..333
FT                   /note="Uncharacterized protein MJ0808"
FT                   /id="PRO_0000107057"
FT   DOMAIN          67..274
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         82
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         86
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         89
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   333 AA;  38337 MW;  C31C2477F6050893 CRC64;
     MREAMFYEKL DDNKVRCHIC PRHCIIKEGE RGFCWNRENI NGVLYAVGYG KVCSLAIDPI
     EKKPLFHFYP TTQVVSLAIG GCNFRCLHCQ NWTISQFPPD EIPYREMTPE EIVEVAIRYN
     CPGISYTYTE PTVYYEFMYD TSVIARENGM FNVMITNGYI EKEPLKALPV DAMNIDIKGN
     ADFYKKVCKA TLEPVLETCK LAKKLGIWVE VTNLIVPNYN DNIDDLLFII HFVRDELGRE
     TPLHFSRFHP DYKLTDVPPT PIETLEMARN LAIEEGLKYV YIGNVPGHEG ENTYCPNCGA
     LLIERYIFNA KIINLDVETK RCKICGEKID IVL