Y818_DROME
ID Y818_DROME Reviewed; 571 AA.
AC P83474; B7YZY8; P83475; Q5U0V3; Q9NK55; Q9VJL2;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 3.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Uncharacterized protein CG42266;
GN ORFNames=CG42266;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10471707; DOI=10.1093/genetics/153.1.179;
RA Ashburner M., Misra S., Roote J., Lewis S.E., Blazej R.G., Davis T.,
RA Doyle C., Galle R.F., George R.A., Harris N.L., Hartzell G., Harvey D.A.,
RA Hong L., Houston K.A., Hoskins R.A., Johnson G., Martin C., Moshrefi A.R.,
RA Palazzolo M., Reese M.G., Spradling A.C., Tsang G., Wan K.H., Whitelaw K.,
RA Celniker S.E., Rubin G.M.;
RT "An exploration of the sequence of a 2.9-Mb region of the genome of
RT Drosophila melanogaster: the Adh region.";
RL Genetics 153:179-219(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Testis;
RA Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Pacleb J.M.,
RA Park S., Wan K.H., Yu C., Rubin G.M., Celniker S.E.;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AE014134; ACL83033.1; -; Genomic_DNA.
DR EMBL; BT016139; AAV37024.1; -; mRNA.
DR RefSeq; NP_001137827.1; NM_001144355.2.
DR AlphaFoldDB; P83474; -.
DR STRING; 7227.FBpp0302857; -.
DR PaxDb; P83474; -.
DR EnsemblMetazoa; FBtr0299599; FBpp0288874; FBgn0259151.
DR GeneID; 7354431; -.
DR KEGG; dme:Dmel_CG42266; -.
DR UCSC; CG42266-RA; d. melanogaster.
DR FlyBase; FBgn0259151; CG42266.
DR VEuPathDB; VectorBase:FBgn0259151; -.
DR eggNOG; ENOG502R8C3; Eukaryota.
DR HOGENOM; CLU_477579_0_0_1; -.
DR InParanoid; P83474; -.
DR OMA; IPNTDCM; -.
DR OrthoDB; 1192073at2759; -.
DR PhylomeDB; P83474; -.
DR BioGRID-ORCS; 7354431; 0 hits in 1 CRISPR screen.
DR ChiTaRS; CG42266; fly.
DR GenomeRNAi; 7354431; -.
DR PRO; PR:P83474; -.
DR Proteomes; UP000000803; Chromosome 2L.
DR Bgee; FBgn0259151; Expressed in testis and 11 other tissues.
DR Genevisible; P83474; DM.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..571
FT /note="Uncharacterized protein CG42266"
FT /id="PRO_0000174339"
FT REGION 71..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..202
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 155
FT /note="W -> F (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 164
FT /note="V -> I (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 184
FT /note="R -> RGYPGPGPRGYPGRGPR (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 189
FT /note="R -> P (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 364
FT /note="R -> T (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 375
FT /note="V -> L (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 498
FT /note="Y -> F (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
FT CONFLICT 522
FT /note="G -> S (in Ref. 4; AAV37024)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 571 AA; 63166 MW; 0944E3160D99E40D CRC64;
MFCEKPTEKR EKSPCRCKNC VLRHSDFLPW PEPIGFTSDR KTDKDNNNHI STLQSVESVV
TISDVNERHT TNHYKNHQSN PDEIAYTPNR SGVSSPVNDG ASSPTQRGGT TPAPQGGKGG
NSPSRVTAQP QAQPTILLIV VNKNDPPPYG QGQSWEYPGQ QYSVPGPRGY PGPGPRGYPG
PGPRGYPGRG PRGYPGPGPR GYPGQGPRRY SCPGPRGYPG PGSSGRPDPG GGLQGYYYPP
SGPGNGTGPS GRPRPQNENE YAYYDRRRYS EAYQNNRNDW RGQPRGYYDG AYAEEHNLNR
QPETRRNCQC PEKQQTPPPE ETQNAQENDD QQTTKRKSFK RLVGMGVGNT CSCQGPSLMG
SNLRSLGNEM DNQEVGRSGN MGTPPNTMEY LSERGSPPEI REVTVTDAKN KTYKCIQVPI
CISTGKANTC RCCKCAPSPD AENDESFDED AECICNHEGK CTCVAGNEFP TEFGCECDLT
NLEQTLRELI PNAECICYLK KKKRRRKRKK WAPKVYYDRF AGPPFVLNPK PRCLDYGRSP
FCNPCYNPCS CAPFAKSCYT CDYNCEGCGR F
