ID   Y821_METMA              Reviewed;         150 AA.
AC   Q8PYP0;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=UPF0292 protein MM_0821 {ECO:0000255|HAMAP-Rule:MF_01095};
GN   OrderedLocusNames=MM_0821;
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA   Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA   Fritz H.-J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01095};
CC       Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_01095};
CC   -!- SIMILARITY: Belongs to the UPF0292 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01095}.
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DR   EMBL; AE008384; AAM30517.1; -; Genomic_DNA.
DR   RefSeq; WP_011032771.1; NC_003901.1.
DR   AlphaFoldDB; Q8PYP0; -.
DR   SMR; Q8PYP0; -.
DR   STRING; 192952.MM_0821; -.
DR   EnsemblBacteria; AAM30517; AAM30517; MM_0821.
DR   GeneID; 44085941; -.
DR   GeneID; 66137782; -.
DR   KEGG; mma:MM_0821; -.
DR   PATRIC; fig|192952.21.peg.973; -.
DR   eggNOG; arCOG01486; Archaea.
DR   HOGENOM; CLU_140789_0_0_2; -.
DR   OMA; VMILTDF; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01027; TOPRIM_RNase_M5_like; 1.
DR   HAMAP; MF_01095; UPF0292; 1.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR034141; TOPRIM_RNase_M5-like.
DR   InterPro; IPR022972; UPF0292.
DR   Pfam; PF13662; Toprim_4; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..150
FT                   /note="UPF0292 protein MM_0821"
FT                   /id="PRO_0000143952"
FT   DOMAIN          28..109
FT                   /note="Toprim"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         34
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         78
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         78
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         80
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
SQ   SEQUENCE   150 AA;  17363 MW;  DE30488735CCDDDC CRC64;
     MTDVDVYRKR LERIEELLLE LSESAERGAV IIVEGKRDIL SMKKLGIKGS FELATRYSLF
     NFSERVASLG CEVIILTDWD RRGDLLAAKL SEYFENFGVK PDLQIRNKLK LISQKEIKDI
     ESLYTYVSKL RVKTGSSLNS EYETNLEFER