Y8236_DICDI
ID Y8236_DICDI Reviewed; 1304 AA.
AC Q54VF4; Q54VF5;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 2.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=TPR-containing protein DDB_G0280363;
GN ORFNames=DDB_G0280363;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SEQUENCE CAUTION:
CC Sequence=EAL67239.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAL67408.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AAFI02000036; EAL67239.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AAFI02000035; EAL67408.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_641155.1; XM_636063.1.
DR RefSeq; XP_641400.1; XM_636308.1.
DR AlphaFoldDB; Q54VF4; -.
DR SMR; Q54VF4; -.
DR STRING; 44689.DDB0206543; -.
DR PaxDb; Q54VF4; -.
DR PRIDE; Q54VF4; -.
DR EnsemblProtists; EAL67239; EAL67239; DDB_G0280519.
DR EnsemblProtists; EAL67408; EAL67408; DDB_G0280363.
DR GeneID; 8622534; -.
DR GeneID; 8622535; -.
DR KEGG; ddi:DDB_G0280363; -.
DR KEGG; ddi:DDB_G0280519; -.
DR dictyBase; DDB_G0280363; -.
DR eggNOG; KOG0495; Eukaryota.
DR InParanoid; Q54VF4; -.
DR PRO; PR:Q54VF4; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045075; Syf1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11246; PTHR11246; 1.
DR SMART; SM00386; HAT; 5.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; SSF48452; 3.
PE 4: Predicted;
KW Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..1304
FT /note="TPR-containing protein DDB_G0280363"
FT /id="PRO_0000352480"
FT REPEAT 769..802
FT /note="TPR 1"
FT REPEAT 899..932
FT /note="TPR 2"
FT REPEAT 978..1011
FT /note="TPR 3"
FT REPEAT 1046..1079
FT /note="TPR 4"
FT REPEAT 1084..1111
FT /note="TPR 5"
FT REPEAT 1112..1150
FT /note="TPR 6"
FT REPEAT 1152..1184
FT /note="TPR 7"
FT REGION 19..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..621
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1304 AA; 152212 MW; 36FFAB1818F89C21 CRC64;
MNNEDSLSYS FGRMMLNQQQ HHHQQQNNTQ VQQQQQQHTT QFNQVRFGGN YHQQHQQQQH
HQQQHHQQQQ QQQQQQQQQQ QHPQQYISPT FSYVHNNSNT SITHGNLYDI DDNQIDNVNI
IRGGNRGYYN QQQQQHQHQQ QQYYHEQQQQ HFNINNNNNN SNNNNNNNNN NNNNNNNNNN
NNNNNNNNNN NNSSLITNSH HAQRIVSPIV NGMTSSSGSN MMINDVSFGM NGISSINGIS
INNGSGDIDE EDDKLLDEQQ QLLQRSLERL SDGEEISFGN PNYFFHPFSE RNINGLPSTN
SSIVSRQQQL QQQQQKLKLK SSPSPISPFF YTQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
QQQQQQQQNT SINGIIKIDQ TPPTPQYIAN PSVSPLNAPI SSPVLGDIYS GNNNNNNINT
NNYRQQQKLN TSTGSYQNMS FDAGVNGFNW SPSLQPDQST STNHTQAMLQ QQQQRQQQQQ
QQTQNLVYLN NQQIKSTVTS NRDHWSSVVK PPPIQLQQNS MQQNPIQQQQ QQQQQQQQQS
LLQHQQMLQM QMQIQQQQQQ QQQQQQQQQQ QQNQQQNQQQ NQQQNQQQNQ QHYPNQHHGQ
HQHNQHNQHH NQHHNQSHPN HKNQHQKQNQ TQQSTQQQQQ QQQNVQTSTT QSPLLQQSQQ
PQQQQPPTSN QRQQQQHNNN TNNVTTINNQ TNINIINNDS DNEELLTTVN HSKPPPNESK
RGELVESPVS KQQYKHFIKQ FKLKEKEGLE IAMEFAFQSL SVLPEKVHWR VYLELADLAN
RQNNLKLARK FYRKVTSTQP YISQGWLEYA KMEEDYGRLE KCQKILQLGL KHCPFNESLL
IKGIRHEEKM DNLEGARALL SQLRDQSIYK TWRAVMEGGL LEARAGNIDV ARKIFKYLMK
HVPWYGPIYQ EAYKLEERCE EYERAINIVE KGLFEDPKYG PLWFSALRLY EKTSHGFLQS
TRNTVERARQ AVSREVTWKI YFEAAQIEER SKNLTLSRAA YVKSVELCPE NLLWKVWLGG
SRTELNADNI CIARKLVFRA LEEVPSKLRS LVLLEYSRLE EYAGNINKSR RILKMAHVEA
RLDWKVFLES VLLEMRANNY EAAIKEAKES LKIHSGAGRL WAALIQLNQL KGVKSQLNVF
KKALQFVPKS GEVWCEGARI ALNNNELREA RRFLEFAIQF TPQFGDSFIE LLRLEIMEKG
PNCDISKLEQ LCINADPNYG FMWLHCTVCV LDSSRQVLRN AKKLLLEMTQ PKEQYLEEKK
PEYGSCWVGS DGVLSLNRVF RNDFNNMSNQ EKRKALFGSD VVKP
