Y827_HAEIN
ID Y827_HAEIN Reviewed; 154 AA.
AC P44886;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Uncharacterized acyl-CoA thioester hydrolase HI_0827;
DE EC=3.1.2.-;
GN OrderedLocusNames=HI_0827;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SIMILARITY: Belongs to the acyl coenzyme A hydrolase family.
CC {ECO:0000305}.
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DR EMBL; L42023; AAC22485.1; -; Genomic_DNA.
DR PIR; A64097; A64097.
DR RefSeq; NP_438987.1; NC_000907.1.
DR RefSeq; WP_005655643.1; NC_000907.1.
DR PDB; 1YLI; X-ray; 1.95 A; A/B=2-154.
DR PDB; 3BJK; X-ray; 1.90 A; A/B/C/D/E/F=2-154.
DR PDBsum; 1YLI; -.
DR PDBsum; 3BJK; -.
DR AlphaFoldDB; P44886; -.
DR SMR; P44886; -.
DR STRING; 71421.HI_0827; -.
DR DrugBank; DB01992; Coenzyme A.
DR EnsemblBacteria; AAC22485; AAC22485; HI_0827.
DR KEGG; hin:HI_0827; -.
DR PATRIC; fig|71421.8.peg.868; -.
DR eggNOG; COG1607; Bacteria.
DR HOGENOM; CLU_050164_2_0_6; -.
DR OMA; MDEMAFL; -.
DR PhylomeDB; P44886; -.
DR BioCyc; HINF71421:G1GJ1-868-MON; -.
DR BRENDA; 3.1.2.20; 2529.
DR EvolutionaryTrace; P44886; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0047617; F:acyl-CoA hydrolase activity; IBA:GO_Central.
DR GO; GO:0036042; F:long-chain fatty acyl-CoA binding; IBA:GO_Central.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR InterPro; IPR040170; Cytosol_ACT.
DR InterPro; IPR033120; HOTDOG_ACOT.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR006683; Thioestr_dom.
DR PANTHER; PTHR11049; PTHR11049; 1.
DR Pfam; PF03061; 4HBT; 1.
DR SUPFAM; SSF54637; SSF54637; 1.
DR PROSITE; PS51770; HOTDOG_ACOT; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Hydrolase; Reference proteome.
FT CHAIN 1..154
FT /note="Uncharacterized acyl-CoA thioester hydrolase
FT HI_0827"
FT /id="PRO_0000053822"
FT DOMAIN 13..128
FT /note="HotDog ACOT-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01106"
FT STRAND 15..22
FT /evidence="ECO:0007829|PDB:3BJK"
FT HELIX 25..27
FT /evidence="ECO:0007829|PDB:3BJK"
FT STRAND 32..34
FT /evidence="ECO:0007829|PDB:3BJK"
FT HELIX 36..55
FT /evidence="ECO:0007829|PDB:3BJK"
FT STRAND 59..69
FT /evidence="ECO:0007829|PDB:3BJK"
FT STRAND 78..88
FT /evidence="ECO:0007829|PDB:3BJK"
FT STRAND 90..102
FT /evidence="ECO:0007829|PDB:3BJK"
FT STRAND 104..108
FT /evidence="ECO:0007829|PDB:3BJK"
FT STRAND 112..125
FT /evidence="ECO:0007829|PDB:3BJK"
FT HELIX 140..149
FT /evidence="ECO:0007829|PDB:3BJK"
SQ SEQUENCE 154 AA; 16763 MW; FF750B2818DFC1DD CRC64;
MSANFTDKNG RQSKGVLLLR TLAMPSDTNA NGDIFGGWIM SQMDMGGAIL AKEIAHGRVV
TVAVESMNFI KPISVGDVVC CYGQCLKVGR SSIKIKVEVW VKKVASEPIG ERYCVTDAVF
TFVAVDNNGR SRTIPRENNQ ELEKALALIS EQPL
