ID   Y829_FRATT              Reviewed;         571 AA.
AC   Q5NGK7;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Uncharacterized transporter FTT_0829c;
GN   OrderedLocusNames=FTT_0829c;
OS   Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=177416;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCHU S4 / Schu 4;
RX   PubMed=15640799; DOI=10.1038/ng1499;
RA   Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H.,
RA   Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D.,
RA   Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S.,
RA   Sjoestedt A., Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W.,
RA   Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W.;
RT   "The complete genome sequence of Francisella tularensis, the causative
RT   agent of tularemia.";
RL   Nat. Genet. 37:153-159(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; AJ749949; CAG45462.1; -; Genomic_DNA.
DR   RefSeq; WP_003020773.1; NZ_CP010290.1.
DR   RefSeq; YP_169835.1; NC_006570.2.
DR   AlphaFoldDB; Q5NGK7; -.
DR   STRING; 177416.FTT_0829c; -.
DR   DNASU; 3191754; -.
DR   EnsemblBacteria; CAG45462; CAG45462; FTT_0829c.
DR   KEGG; ftu:FTT_0829c; -.
DR   eggNOG; COG2985; Bacteria.
DR   OMA; RDGKNYF; -.
DR   Proteomes; UP000001174; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   InterPro; IPR022457; Asp_Ala_antiprt.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR03802; Asp_Ala_antiprt; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..571
FT                   /note="Uncharacterized transporter FTT_0829c"
FT                   /id="PRO_0000208773"
FT   TRANSMEM        5..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        391..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        412..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        455..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        484..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        513..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        547..569
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   571 AA;  62436 MW;  C8AE6E0BB4C43ABC CRC64;
     MFHEVILNVL KNPFIALFLT LSLGYLVGKI KYKTFVLGGI SGSLIIGVII GQLNITISPD
     IGSLFFALFI YAGGYQGGAQ FFRSLNKDTL LLLASSTITC VLGLLCVLVF AWIFQLDKGT
     AAGLGAGGLT QSAMIGSANN AIAMINSVSE STIHTMQTNV TVGYAVCYIF GSFGPIILLA
     TIFPLVMKWD LRKEAIKLAT EQSDGNLDLE VGQFSAFSEY TTRAYKINRD SQLLGKSLVE
     VYKTYKYKVV IKNIIRDNKL LTITPETTIN TNDIVAITFY ADLDIQSIIS KDIEVTKPEQ
     FNFIEEKRSL ILTNKNLFNK TIKEVKDIIQ DRNYYGVFLQ KIIRSGQKLP ISDDLKLRRG
     DEIRLIGKPE DLDKISNKIG TFISEAPITD FIFFGLGMVL GYIFGLISFN IFGISITLGA
     GVDCLLSGLI FGWIRSIKPQ FSNLPVGASN FIRDLGLAIF VASVGITAGP QAITTIKEHG
     LTLFFLGIGV TIIPQVISFY ISYYLLKIKN PIVLLATIAG GRSVNPGFAA LLERAGNATP
     VIPFTSSYAL ANIWLTLWGP VIVALVTIIP K