ID   Y8387_DICDI             Reviewed;         257 AA.
AC   Q54QJ8;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Uncharacterized protein DDB_G0283871;
GN   ORFNames=DDB_G0283871;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA   Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA   Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT   "Changing patterns of gene expression in Dictyostelium prestalk cell
RT   subtypes recognized by in situ hybridization with genes from microarray
RT   analyses.";
RL   Eukaryot. Cell 2:627-637(2003).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=15470642; DOI=10.1387/ijdb.041862ns;
RA   Shimada N., Maeda M., Urushihara H., Kawata T.;
RT   "Identification of new modes of Dd-STATa regulation of gene expression in
RT   Dictyostelium by in situ hybridisation.";
RL   Int. J. Dev. Biol. 48:679-682(2004).
RN   [4]
RP   INDUCTION [LARGE SCALE ANALYSIS].
RX   PubMed=18559084; DOI=10.1186/1471-2164-9-291;
RA   Sillo A., Bloomfield G., Balest A., Balbo A., Pergolizzi B., Peracino B.,
RA   Skelton J., Ivens A., Bozzaro S.;
RT   "Genome-wide transcriptional changes induced by phagocytosis or growth on
RT   bacteria in Dictyostelium.";
RL   BMC Genomics 9:291-291(2008).
CC   -!- DEVELOPMENTAL STAGE: Expressed in prestalk pstO cells but not in pstA
CC       cells. Strongly expressed throughout development. Expressed normally in
CC       dmtA-null cells. {ECO:0000269|PubMed:12796308}.
CC   -!- INDUCTION: Down-regulated by phagocytic stimuli.
CC       {ECO:0000269|PubMed:18559084}.
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DR   EMBL; AAFI02000057; EAL65550.1; -; Genomic_DNA.
DR   RefSeq; XP_638873.1; XM_633781.1.
DR   AlphaFoldDB; Q54QJ8; -.
DR   SMR; Q54QJ8; -.
DR   PaxDb; Q54QJ8; -.
DR   EnsemblProtists; EAL65550; EAL65550; DDB_G0283871.
DR   GeneID; 8624271; -.
DR   KEGG; ddi:DDB_G0283871; -.
DR   dictyBase; DDB_G0283871; -.
DR   HOGENOM; CLU_1083494_0_0_1; -.
DR   InParanoid; Q54QJ8; -.
DR   OMA; WIATHIA; -.
DR   PRO; PR:Q54QJ8; -.
DR   Proteomes; UP000002195; Chromosome 4.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..257
FT                   /note="Uncharacterized protein DDB_G0283871"
FT                   /id="PRO_0000392663"
SQ   SEQUENCE   257 AA;  29838 MW;  A9EE4B429E1DDC33 CRC64;
     MEAKTQFELI TIKSEDGFDE NELSVLLKSD SDFHMNGFIW GHLAAKHVYS KLNSKLKSFE
     PKSRSEINEM IKAITAVTEF IEVHYYHEEE IAWKFLIEQQ QCLSEPLLTI VKPQHTQWTE
     INNEMKDLVK SLTENQEIKD KSSNGWTESI SKVKEILQKL TAMVYKSFYD EERIIIPVVL
     SSIPKSKQNK LGEKMNETMK NAPTSKFVLG AILDVCKTNK DLDENVKKAI PWAVRKVIFP
     LALEKNYNWF SEFVEIK