ID   Y839_TREPA              Reviewed;         335 AA.
AC   O83811;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Uncharacterized lipoprotein TP_0839;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0839;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
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DR   EMBL; AE000520; AAC65809.1; -; Genomic_DNA.
DR   PIR; D71275; D71275.
DR   RefSeq; WP_010882283.1; NC_021490.2.
DR   AlphaFoldDB; O83811; -.
DR   STRING; 243276.TPANIC_0839; -.
DR   EnsemblBacteria; AAC65809; AAC65809; TP_0839.
DR   GeneID; 57879356; -.
DR   KEGG; tpa:TP_0839; -.
DR   HOGENOM; CLU_828859_0_0_12; -.
DR   OMA; QAYPHTI; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025164; DUF4097.
DR   Pfam; PF13349; DUF4097; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           22..335
FT                   /note="Uncharacterized lipoprotein TP_0839"
FT                   /id="PRO_0000014264"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   335 AA;  37365 MW;  2F4C5FE154DAB869 CRC64;
     MDKKARAHTV IVCLVGALSL ACAYLLGGSM KYLRGDVSRF WTSSRMQRHP AHSSQPVVRT
     FTDADGYTCL DQAHPHTIVI DATRVRVSVQ VCAQRRSLAY KVVKNSVYDP LSIHLDPTML
     VLRRGKKTVR ESTPPADSPG VMQSALNVRD TLRDWFYTFW KNVWGSRWGH SVVPIEAIIC
     VPAQHNVHNL KVRVKDSSLR LEGIEVRFAD VYAHASELKL NGVRTDRTLL HTTDGDTQCS
     RCVLSDAHLY TDRGTLSFDG TLQGNSEIGT RTGTVVARFT ERQSYYALSV FSGHGAVYIN
     DQRVRKTLGT CLSTGGSAQL CVRNERGVLH VYFPQ