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Y841_METTH
ID   Y841_METTH              Reviewed;         343 AA.
AC   O26929;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Uncharacterized transporter MTH_841;
GN   OrderedLocusNames=MTH_841;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB85339.1; -; Genomic_DNA.
DR   PIR; C69212; C69212.
DR   RefSeq; WP_010876474.1; NC_000916.1.
DR   AlphaFoldDB; O26929; -.
DR   SMR; O26929; -.
DR   STRING; 187420.MTH_841; -.
DR   EnsemblBacteria; AAB85339; AAB85339; MTH_841.
DR   GeneID; 1471249; -.
DR   KEGG; mth:MTH_841; -.
DR   PATRIC; fig|187420.15.peg.824; -.
DR   HOGENOM; CLU_042632_1_0_2; -.
DR   OMA; EPHSHWH; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000620; EamA_dom.
DR   Pfam; PF00892; EamA; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..343
FT                   /note="Uncharacterized transporter MTH_841"
FT                   /id="PRO_0000108207"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          55..192
FT                   /note="EamA 1"
FT   DOMAIN          216..340
FT                   /note="EamA 2"
SQ   SEQUENCE   343 AA;  37839 MW;  4296C7890CB91B7F CRC64;
     MLSYPGELQG CRVILYLVGH HLYLIPTTIS MCGCPEEGAY MRRLWGYISI ITATIFFGIS
     ATLDKIMLSS MHPVTIGAYT YIIAGIFLFF IRETPLREHV LNAINRKGES EARIKRNDYL
     ILLLTALLST VIAPLLFLTG LGDTTAVNAS LILNVEVLFI ILLGYLIFRE TLQLKDFLGI
     VLIILGAVYL LTEGDFSTIL RNVAVTGNFL VMAAAFFWSL DTVLSKFLSR KRDLIFISGV
     KSSVGGFVLL IIMLILGINT ELPLEMLPYA LGVSVFSIGC SFILIYIAIR EIGASMVGAL
     FPLSSLFGAI FAFIILREPF SIMQGISGIV MLTGVFILYW NGK
 
 
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