Y841_METTH
ID Y841_METTH Reviewed; 343 AA.
AC O26929;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Uncharacterized transporter MTH_841;
GN OrderedLocusNames=MTH_841;
OS Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX NCBI_TaxID=187420;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA Reeve J.N.;
RT "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT functional analysis and comparative genomics.";
RL J. Bacteriol. 179:7135-7155(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR EMBL; AE000666; AAB85339.1; -; Genomic_DNA.
DR PIR; C69212; C69212.
DR RefSeq; WP_010876474.1; NC_000916.1.
DR AlphaFoldDB; O26929; -.
DR SMR; O26929; -.
DR STRING; 187420.MTH_841; -.
DR EnsemblBacteria; AAB85339; AAB85339; MTH_841.
DR GeneID; 1471249; -.
DR KEGG; mth:MTH_841; -.
DR PATRIC; fig|187420.15.peg.824; -.
DR HOGENOM; CLU_042632_1_0_2; -.
DR OMA; EPHSHWH; -.
DR Proteomes; UP000005223; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR000620; EamA_dom.
DR Pfam; PF00892; EamA; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..343
FT /note="Uncharacterized transporter MTH_841"
FT /id="PRO_0000108207"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 55..192
FT /note="EamA 1"
FT DOMAIN 216..340
FT /note="EamA 2"
SQ SEQUENCE 343 AA; 37839 MW; 4296C7890CB91B7F CRC64;
MLSYPGELQG CRVILYLVGH HLYLIPTTIS MCGCPEEGAY MRRLWGYISI ITATIFFGIS
ATLDKIMLSS MHPVTIGAYT YIIAGIFLFF IRETPLREHV LNAINRKGES EARIKRNDYL
ILLLTALLST VIAPLLFLTG LGDTTAVNAS LILNVEVLFI ILLGYLIFRE TLQLKDFLGI
VLIILGAVYL LTEGDFSTIL RNVAVTGNFL VMAAAFFWSL DTVLSKFLSR KRDLIFISGV
KSSVGGFVLL IIMLILGINT ELPLEMLPYA LGVSVFSIGC SFILIYIAIR EIGASMVGAL
FPLSSLFGAI FAFIILREPF SIMQGISGIV MLTGVFILYW NGK