ID   Y846_CAMJE              Reviewed;         374 AA.
AC   Q9PP77; Q0PA44;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Uncharacterized metallophosphoesterase Cj0846;
DE            EC=3.1.-.-;
GN   OrderedLocusNames=Cj0846;
OS   Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC
OS   11168).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=192222;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700819 / NCTC 11168;
RX   PubMed=10688204; DOI=10.1038/35001088;
RA   Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M.,
RA   Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S.,
RA   Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A.,
RA   Rajandream M.A., Rutherford K.M., van Vliet A.H.M., Whitehead S.,
RA   Barrell B.G.;
RT   "The genome sequence of the food-borne pathogen Campylobacter jejuni
RT   reveals hypervariable sequences.";
RL   Nature 403:665-668(2000).
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000250};
CC       Note=Binds 2 divalent metal cations. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL111168; CAL34974.1; -; Genomic_DNA.
DR   PIR; F81357; F81357.
DR   RefSeq; WP_002871823.1; NC_002163.1.
DR   RefSeq; YP_002344253.1; NC_002163.1.
DR   AlphaFoldDB; Q9PP77; -.
DR   SMR; Q9PP77; -.
DR   IntAct; Q9PP77; 4.
DR   STRING; 192222.Cj0846; -.
DR   PaxDb; Q9PP77; -.
DR   PRIDE; Q9PP77; -.
DR   DNASU; 905145; -.
DR   EnsemblBacteria; CAL34974; CAL34974; Cj0846.
DR   GeneID; 905145; -.
DR   KEGG; cje:Cj0846; -.
DR   PATRIC; fig|192222.6.peg.834; -.
DR   eggNOG; COG1408; Bacteria.
DR   HOGENOM; CLU_025443_0_1_7; -.
DR   OMA; DTHYGPI; -.
DR   Proteomes; UP000000799; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Metal-binding; Reference proteome.
FT   CHAIN           1..374
FT                   /note="Uncharacterized metallophosphoesterase Cj0846"
FT                   /id="PRO_0000172853"
FT   BINDING         158
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         160
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         190
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         190
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         221
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         312
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         314
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   374 AA;  42849 MW;  30DE681899139004 CRC64;
     MIFLIFSFIV LLIFGLANVY IYKRLIKKIT LFKYFYKIFS FIFIVLFLAQ AVFLIFRRDE
     YLSDTWYEIL AMFYAPTYCL FFMTLAWDFV KLILALMGKR DKTYNLILRL IFELSLIVLS
     VFLIYASINN ALKTPEVKSV DVEIPNLKKD LKIVMLTDIH LGKNLHENFL DKLITKVNLQ
     SPDMVVIVGD LIDTNPKDLK NYISKLNDFN STYGTFYALG NHEYYHGINE VLDLLRKHTN
     MKILVNQNLD LGFIDIAGLG DLAGLDRGLY APDLARIKVD LNTSKASILL THQPKTALLY
     DLSDFDLVLS GHTHGGQIFP FMFLVKLQQG FVHGLYDLGE KTKLYVSSGA GFWGPSLRVF
     APSEIVILNL KGKK