ID   Y854_ENCCU              Reviewed;         291 AA.
AC   Q8SUS0;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Uncharacterized membrane protein ECU08_0540;
GN   OrderedLocusNames=ECU08_0540;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL
RP   STAGE, AND SUBCELLULAR LOCATION.
RX   PubMed=16691553; DOI=10.1002/pmic.200500796;
RA   Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.;
RT   "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi
RT   (microsporidia): a reference map for proteins expressed in late sporogonial
RT   stages.";
RL   Proteomics 6:3625-3635(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in late sporogonial stages.
CC       {ECO:0000269|PubMed:16691553}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL590448; CAD26359.1; -; Genomic_DNA.
DR   RefSeq; NP_597183.1; NM_001041792.1.
DR   AlphaFoldDB; Q8SUS0; -.
DR   GeneID; 859605; -.
DR   KEGG; ecu:ECU08_0540; -.
DR   VEuPathDB; MicrosporidiaDB:ECU08_0540; -.
DR   HOGENOM; CLU_871627_0_0_1; -.
DR   OrthoDB; 1558156at2759; -.
DR   Proteomes; UP000000819; Chromosome VIII.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..291
FT                   /note="Uncharacterized membrane protein ECU08_0540"
FT                   /id="PRO_0000383037"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          269..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        249
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   291 AA;  31903 MW;  70ABBB450CD45D35 CRC64;
     MSKMDKLAKF EKFDLFFAAI ACICGILKVM EMGKEGYPTL GTVSKNGMAV LAVLVALGFL
     LKYADQMCRR ITSHSFSEKG GFLNPCVILS VIEFFMMLIC IKAMLFYPAE IPGVDDSSQM
     EPPISSKFGL FGAIFMPYIF AECIRLLLAN KNSRRDRVIL GILVLGCLAM AGLAYLEYKG
     KGNFISAGIL GVGLSMLLSR LALVDEDEED TLLDDSAEGG NVWMYLAMFA SFTLVLILLA
     RSHRILFDNL SFLDSLKSFT FLGRKVSQMA SEDPPKDPLP RQEGGGGDTI A