ID   Y857_STRP6              Reviewed;          61 AA.
AC   Q5XC71;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Probable tautomerase M6_Spy0857;
DE            EC=5.3.2.-;
GN   OrderedLocusNames=M6_Spy0857;
OS   Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=286636;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-946 / MGAS10394;
RX   PubMed=15272401; DOI=10.1086/422697;
RA   Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA   Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT   "Progress toward characterization of the group A Streptococcus metagenome:
RT   complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL   J. Infect. Dis. 190:727-738(2004).
CC   -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family.
CC       {ECO:0000305}.
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DR   EMBL; CP000003; AAT86992.1; -; Genomic_DNA.
DR   RefSeq; WP_002984671.1; NC_006086.1.
DR   AlphaFoldDB; Q5XC71; -.
DR   SMR; Q5XC71; -.
DR   EnsemblBacteria; AAT86992; AAT86992; M6_Spy0857.
DR   GeneID; 57852627; -.
DR   KEGG; spa:M6_Spy0857; -.
DR   HOGENOM; CLU_148073_5_1_9; -.
DR   OMA; HIMINDM; -.
DR   Proteomes; UP000001167; Chromosome.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.429.10; -; 1.
DR   InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR   InterPro; IPR014347; Tautomerase/MIF_sf.
DR   Pfam; PF01361; Tautomerase; 1.
DR   SUPFAM; SSF55331; SSF55331; 1.
PE   3: Inferred from homology;
KW   Isomerase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..61
FT                   /note="Probable tautomerase M6_Spy0857"
FT                   /id="PRO_0000209557"
FT   ACT_SITE        2
FT                   /note="Proton acceptor; via imino nitrogen"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   61 AA;  7055 MW;  689FE80C7CC05754 CRC64;
     MPFVTIDLFE GRSQEQKNQL AREVTEVVSR IAKAPKENIH VFINDMPEGT YYPQGEMKQK
     S