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Y8602_DICDI
ID   Y8602_DICDI             Reviewed;         218 AA.
AC   Q54ME0;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Uncharacterized protein DDB_G0286021;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0286021;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=12963116; DOI=10.1016/s0925-4773(03)00136-9;
RA   Muramoto T., Suzuki K., Shimizu H., Kohara Y., Kohriki E., Obara S.,
RA   Tanaka Y., Urushihara H.;
RT   "Construction of a gamete-enriched gene pool and RNAi-mediated functional
RT   analysis in Dictyostelium discoideum.";
RL   Mech. Dev. 120:965-975(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in gametes.
CC       {ECO:0000269|PubMed:12963116}.
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DR   EMBL; AAFI02000085; EAL64389.1; -; Genomic_DNA.
DR   RefSeq; XP_637894.1; XM_632802.1.
DR   AlphaFoldDB; Q54ME0; -.
DR   SMR; Q54ME0; -.
DR   PaxDb; Q54ME0; -.
DR   EnsemblProtists; EAL64389; EAL64389; DDB_G0286021.
DR   GeneID; 8625404; -.
DR   KEGG; ddi:DDB_G0286021; -.
DR   dictyBase; DDB_G0286021; -.
DR   eggNOG; ENOG502RHA4; Eukaryota.
DR   HOGENOM; CLU_1268922_0_0_1; -.
DR   InParanoid; Q54ME0; -.
DR   OMA; NWMDNYG; -.
DR   PhylomeDB; Q54ME0; -.
DR   PRO; PR:Q54ME0; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR013201; Prot_inhib_I29.
DR   Pfam; PF08246; Inhibitor_I29; 1.
DR   SMART; SM00848; Inhibitor_I29; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..218
FT                   /note="Uncharacterized protein DDB_G0286021"
FT                   /id="PRO_0000393120"
FT   TOPO_DOM        20..146
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        168..218
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   218 AA;  23710 MW;  7AA9DE6D328091E7 CRC64;
     MKIIVLVLLI LGCSQLINSQ EVPSDSILFQ QFINWMDNYG IFYTSGDMQS KFKSWKSNVL
     EIASLNSNLN VPDVLYTVTE TPVSNLRTLL DAEPTIVESY PGQDIQQFEV NQFSDLTASE
     FSNIYAGADA SLAISEVAAS TLSTGAIVGI AVGGSVALIG ATAATVLIVK KKRQNKKPQV
     SEPIATTQDV KMKPTNGIDL LNRTENQHRS ITARAFYS
 
 
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