ID   Y860_MYCLE              Reviewed;         307 AA.
AC   O32960;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Epimerase family protein ML0860;
GN   OrderedLocusNames=ML0860; ORFNames=MLCB22.18;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. SDR39U1 subfamily. {ECO:0000305}.
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DR   EMBL; Z98741; CAB11383.1; -; Genomic_DNA.
DR   EMBL; AL583920; CAC31241.1; -; Genomic_DNA.
DR   PIR; T44893; T44893.
DR   RefSeq; NP_301648.1; NC_002677.1.
DR   RefSeq; WP_010907972.1; NC_002677.1.
DR   AlphaFoldDB; O32960; -.
DR   SMR; O32960; -.
DR   STRING; 272631.ML0860; -.
DR   EnsemblBacteria; CAC31241; CAC31241; CAC31241.
DR   KEGG; mle:ML0860; -.
DR   PATRIC; fig|272631.5.peg.1586; -.
DR   Leproma; ML0860; -.
DR   eggNOG; COG1090; Bacteria.
DR   HOGENOM; CLU_047373_0_2_11; -.
DR   OMA; YMPWIHI; -.
DR   Proteomes; UP000000806; Chromosome.
DR   InterPro; IPR013549; DUF1731.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR010099; SDR39U1.
DR   Pfam; PF08338; DUF1731; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01777; yfcH; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..307
FT                   /note="Epimerase family protein ML0860"
FT                   /id="PRO_0000162406"
SQ   SEQUENCE   307 AA;  32853 MW;  EEFE5BA102455DA2 CRC64;
     MAQASRKAVV AIAGSSGMIG SALAAALRAN DHLVLRIVRR TPANAEELHW NPESGEFDTD
     AITDVDAVVN LCGVNLGQRR WSGSFKQNLR DSRITPTEVL SAAVAEAGVK TFINASAVGY
     YGNTRDRVVD ENDRAGTGFL AQLCQDWEGA TLPAQYAGTR VILARTGMVL AQEAGVLSRM
     RPLFSFALGA RIGNGRQYMS WISLEDEVRA LLFAISHQSL SGPLNLTGPA PVTNAEFTTA
     FGRAINRPTP LMLPSFAVRA ALGEFADEGL LIGQRAIPAA LERAGFQFHH NTIGEALSYA
     TTRPSQN