ID   Y8625_DICDI             Reviewed;        1143 AA.
AC   Q54GV8;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Uncharacterized transmembrane protein DDB_G0289901;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0289901;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000149; EAL62463.1; -; Genomic_DNA.
DR   RefSeq; XP_635961.1; XM_630869.1.
DR   AlphaFoldDB; Q54GV8; -.
DR   STRING; 44689.DDB0302663; -.
DR   PaxDb; Q54GV8; -.
DR   EnsemblProtists; EAL62463; EAL62463; DDB_G0289901.
DR   GeneID; 8627376; -.
DR   KEGG; ddi:DDB_G0289901; -.
DR   dictyBase; DDB_G0289901; -.
DR   eggNOG; ENOG502RIK7; Eukaryota.
DR   HOGENOM; CLU_277494_0_0_1; -.
DR   OMA; HANAYNG; -.
DR   PRO; PR:Q54GV8; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..1143
FT                   /note="Uncharacterized transmembrane protein DDB_G0289901"
FT                   /id="PRO_0000346938"
FT   TOPO_DOM        21..1121
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1122..1142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        1143
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          177..1120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..1109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1143 AA;  101668 MW;  57CA9836286ECE53 CRC64;
     MKLLLLALIL VLSNINLISG NGLVWPHPRL PCSPYDERGC INTQKCSSTD CDSFKRRIYF
     DVAYNTAFTI YQHTIFKYYS ANYYKVELIV GGKVYFIHKF GQFRGDDCEF DEIIPAFYKK
     VQFLDLSTPI KATIQFSFDF SSHPKHANIY YSCIDVWLFD SAYYNYCPTN SGGGSGNSGG
     SWSSGGSGNS GGGWSSGGSG NSGGSWSSGN SGGHSTGDCP TSSGGWTSGS HSSGSWSSGG
     GSGSSSGGQS SGSWSSGGGS SSGGHSSGSW SSGGGSSAGG GSSSGSHSSG SWSSGGSSSG
     GQSSGSWSSG GGSSSGGQSS GSWSSGGGSS SGSHSSGSWS SGGSSSGSHS SGSWSSGGSS
     SSSGNSGWMT ASGGNTGGNT GGNTGGNTGG QSSGNSGWMT ASGGNTGGNT GGNTGGQSSG
     NSGWMTASGG NTGGNTGGNT GGQSSGSSSS GGNSGWLTSS GSNSGSSSSG SNSGWLTSSG
     NSVSSSSGGN SGWLTSSGGN SGGNSGSSSS GGNSGWLTSS GGNSGGSSSS GSNSGASSSG
     DNTGGNSGWL TSSGGNTGGN SGAATGGNSG GNSGASSSGG NSGGASSSGG NTGGNSGWLT
     SSGGNTGGNS GAATGGNSGG NSGASSSGGN SGWLTGGVTG GNSGGATGGN SGGATGGNSG
     GATGGNSGGA TGGNSGGASS SGGNSGGATG GNSGGATGGN SGGATGGNSG GATGGNSGGA
     TGGNSGGATG GNSGGASSSG GNTGGNSGGA TGGNSGGATG GNSGGATGGN SGGATGGNSG
     GNSGASSSGG NSGWLTGGAT GGNSGGATGG NSGAATGGNS GATGGNSGGN SGAATGGNIG
     GASSGSSSSG GNSGWLTGGA TGGNSGGATG GNSGGATGGN SGGATGGNSG GATGGNSGGA
     TGGNSGAATG ANSGAATGAN SGAATGANSG AATGANSGNN AAVTGAANGN NGAAAGANSG
     AATAANSGAA TAANSGAATA ANRGNNAAAT GAANGNNGAA AGANSGAATA ANSGAANSGA
     ATAANSGAAA GANSGAATAA NSGAATAASG GNGASGAANP GSIVTPNDQN VSPLSNSDAA
     ATAASTTGRN PRNPTSRAPT VTPTPTSSAE EPAAGGEDSS AISKYSIQSF GIFVLSMIIY
     LVI