ID   Y8631_DICDI             Reviewed;         382 AA.
AC   Q54YK1;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 2.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Putative UDP-sugar transporter DDB_G0278631;
GN   ORFNames=DDB_G0278631;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May be nvolved in the import of UDP-sugars. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TPT transporter family. SLC35D subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000023; EAL68488.2; -; Genomic_DNA.
DR   RefSeq; XP_642201.2; XM_637109.2.
DR   AlphaFoldDB; Q54YK1; -.
DR   SMR; Q54YK1; -.
DR   STRING; 44689.DDB0252849; -.
DR   PaxDb; Q54YK1; -.
DR   EnsemblProtists; EAL68488; EAL68488; DDB_G0278631.
DR   GeneID; 8621408; -.
DR   KEGG; ddi:DDB_G0278631; -.
DR   dictyBase; DDB_G0278631; -.
DR   eggNOG; KOG1444; Eukaryota.
DR   HOGENOM; CLU_724471_0_0_1; -.
DR   InParanoid; Q54YK1; -.
DR   OMA; ERTINFP; -.
DR   PhylomeDB; Q54YK1; -.
DR   PRO; PR:Q54YK1; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004853; Sugar_P_trans_dom.
DR   Pfam; PF03151; TPT; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..382
FT                   /note="Putative UDP-sugar transporter DDB_G0278631"
FT                   /id="PRO_0000376851"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   382 AA;  43694 MW;  362A9701134A2E80 CRC64;
     MKLKPNDIYI PLNSIQFKIH HNDINIKYDT EEDNNNNNNN NNNNRYIDDN EKMKISEDES
     IFKSINNDNK NQQNDNIINS FNRGSNSFLF NIINFYKSPR FLSGGAVLLY VMTTYDFSAS
     NFLLFNQMVV TIVILHILKH FNILKINTNF EKETIKKLMP LSFCYIINVL LGLDSLKQLN
     IPMYSALKRL VAVVILVMEY FILKKVSPPK IIASVVVMVI GAVVAGITDL SFNSLGYSLV
     LLSCIFQASY LIYVKKVASN MSTYDMLYYN SVLSLPITIF LMIVNQEIEY FQTFEHLYDS
     SFQAYFILSI FLGFFLNFCI FFCTSVNSPL TTSVTGQVKN IASTIIGAMV FNDIIIHPIN
     ILGLIINIIG SIWYSFLKLT SK