ID   Y874_MYCTU              Reviewed;         386 AA.
AC   P9WKR9; L0T7Z3; P0A5D3; Q10536;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Uncharacterized protein Rv0874c;
GN   OrderedLocusNames=Rv0874c; ORFNames=MTCY31.02c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv0628c. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43622.1; -; Genomic_DNA.
DR   PIR; G70779; G70779.
DR   RefSeq; NP_215389.1; NC_000962.3.
DR   RefSeq; WP_003404586.1; NZ_NVQJ01000001.1.
DR   AlphaFoldDB; P9WKR9; -.
DR   STRING; 83332.Rv0874c; -.
DR   PaxDb; P9WKR9; -.
DR   DNASU; 885658; -.
DR   GeneID; 885658; -.
DR   KEGG; mtu:Rv0874c; -.
DR   TubercuList; Rv0874c; -.
DR   eggNOG; COG4398; Bacteria.
DR   OMA; HLYGYTG; -.
DR   PhylomeDB; P9WKR9; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019494; FIST_C.
DR   InterPro; IPR013702; FIST_domain_N.
DR   InterPro; IPR016741; UCP018953.
DR   Pfam; PF08495; FIST; 1.
DR   Pfam; PF10442; FIST_C; 1.
DR   PIRSF; PIRSF018953; UCP018953; 1.
DR   SMART; SM00897; FIST; 1.
DR   SMART; SM01204; FIST_C; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..386
FT                   /note="Uncharacterized protein Rv0874c"
FT                   /id="PRO_0000103717"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   386 AA;  40402 MW;  6BA71B4ACDAA190C CRC64;
     MRIGVGVCTT PDARQAAVEA AGQARDELAG EAPSLAVLLG SRAHTDRAAD VLSAVLQMID
     PPALVGCIAQ AIVAGRHEIE DEPAVVVWLA SGLAAETFQL DFVRTGSGAL ITGYRFDRTA
     RDLHLLLPDP YTFPSNLLIE HPNTDLPGTA VVGGVVSGGR RRGDTRLFRD HDVLTSGVVG
     VRLPGMRGVP VVSQGCRPIG YPYIVTGADG ILITELGGRP PLQRLREIVE GLSPDERALV
     SHGLQIGIVV DEHLAAPGQG DFVIRGLLGA DPSTGSIEID EVVQVGATMQ FQVRDAAGAD
     KDLRLTVERA AARLPGRAAG ALLFTCNGRG RRMFGVADHD ASTIEELLGG IPLAGFFAAG
     EIGPIAGRNA LHGFTASMAL FVDDME