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Y878_HAEIN
ID   Y878_HAEIN              Reviewed;         306 AA.
AC   P71360;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized transporter HI_0878;
GN   OrderedLocusNames=HI_0878;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22534.1; -; Genomic_DNA.
DR   RefSeq; NP_439039.1; NC_000907.1.
DR   RefSeq; WP_005693231.1; NC_000907.1.
DR   AlphaFoldDB; P71360; -.
DR   SMR; P71360; -.
DR   STRING; 71421.HI_0878; -.
DR   EnsemblBacteria; AAC22534; AAC22534; HI_0878.
DR   KEGG; hin:HI_0878; -.
DR   PATRIC; fig|71421.8.peg.920; -.
DR   eggNOG; COG0697; Bacteria.
DR   HOGENOM; CLU_074108_1_0_6; -.
DR   OMA; FCGANTL; -.
DR   PhylomeDB; P71360; -.
DR   BioCyc; HINF71421:G1GJ1-918-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000620; EamA_dom.
DR   Pfam; PF00892; EamA; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..306
FT                   /note="Uncharacterized transporter HI_0878"
FT                   /id="PRO_0000108172"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          17..142
FT                   /note="EamA 1"
FT   DOMAIN          166..296
FT                   /note="EamA 2"
SQ   SEQUENCE   306 AA;  33893 MW;  AAB056682DA10CDF CRC64;
     MKQQPLLGFT FALITAMAWG SLPIALKQVL SVMNAQTIVW YRFIIAAVSL LALLAYKKQL
     PELMKVRQYA WIMLIGVIGL TSNFLLFSSS LNYIEPSVAQ IFIHLSSFGM LICGVLIFKE
     KLGLHQKIGL FLLLIGLGLF FNDRFDAFAG LNQYSTGVIL GVGGALIWVA YGMAQKLMLR
     KFNSQQILLM MYLGCAIAFM PMADFSQVQE LTPLALICFI YCCLNTLIGY GSYAEALNRW
     DVSKVSVVIT LVPLFTILFS HIAHYFSPAD FAAPELNNIS YIGAFVVVCG AILSAIGHKL
     LPHKNH
 
 
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