Y878_HAEIN
ID Y878_HAEIN Reviewed; 306 AA.
AC P71360;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Uncharacterized transporter HI_0878;
GN OrderedLocusNames=HI_0878;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR EMBL; L42023; AAC22534.1; -; Genomic_DNA.
DR RefSeq; NP_439039.1; NC_000907.1.
DR RefSeq; WP_005693231.1; NC_000907.1.
DR AlphaFoldDB; P71360; -.
DR SMR; P71360; -.
DR STRING; 71421.HI_0878; -.
DR EnsemblBacteria; AAC22534; AAC22534; HI_0878.
DR KEGG; hin:HI_0878; -.
DR PATRIC; fig|71421.8.peg.920; -.
DR eggNOG; COG0697; Bacteria.
DR HOGENOM; CLU_074108_1_0_6; -.
DR OMA; FCGANTL; -.
DR PhylomeDB; P71360; -.
DR BioCyc; HINF71421:G1GJ1-918-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR000620; EamA_dom.
DR Pfam; PF00892; EamA; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..306
FT /note="Uncharacterized transporter HI_0878"
FT /id="PRO_0000108172"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 17..142
FT /note="EamA 1"
FT DOMAIN 166..296
FT /note="EamA 2"
SQ SEQUENCE 306 AA; 33893 MW; AAB056682DA10CDF CRC64;
MKQQPLLGFT FALITAMAWG SLPIALKQVL SVMNAQTIVW YRFIIAAVSL LALLAYKKQL
PELMKVRQYA WIMLIGVIGL TSNFLLFSSS LNYIEPSVAQ IFIHLSSFGM LICGVLIFKE
KLGLHQKIGL FLLLIGLGLF FNDRFDAFAG LNQYSTGVIL GVGGALIWVA YGMAQKLMLR
KFNSQQILLM MYLGCAIAFM PMADFSQVQE LTPLALICFI YCCLNTLIGY GSYAEALNRW
DVSKVSVVIT LVPLFTILFS HIAHYFSPAD FAAPELNNIS YIGAFVVVCG AILSAIGHKL
LPHKNH