ID   Y878_TREPA              Reviewed;         316 AA.
AC   O83848;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Uncharacterized protein TP_0878;
GN   OrderedLocusNames=TP_0878;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65848.1; -; Genomic_DNA.
DR   PIR; D71271; D71271.
DR   RefSeq; WP_010882321.1; NC_021490.2.
DR   AlphaFoldDB; O83848; -.
DR   STRING; 243276.TPANIC_0878; -.
DR   EnsemblBacteria; AAC65848; AAC65848; TP_0878.
DR   KEGG; tpa:TP_0878; -.
DR   eggNOG; ENOG5031CDY; Bacteria.
DR   HOGENOM; CLU_871360_0_0_12; -.
DR   OMA; CIDIFPA; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025641; DUF4340.
DR   Pfam; PF14238; DUF4340; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..316
FT                   /note="Uncharacterized protein TP_0878"
FT                   /id="PRO_0000202345"
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   316 AA;  37313 MW;  C66A98B541CBC88E CRC64;
     MRSVDSRSSV TRWVCLTSVI LFCFCIAVMR YGGVKKRRYF YGFCLHPRER ADITEVILRF
     PREERNASRE LRWVKKDRQW FIQLAHAIHP AKQEVLERLF QYLFTKRRFE FITNNTRFFS
     DYALGKQPAV QMKFTKKNGA AIGDIYFGAL NGTGLGRYIR IGDNAAVFLT EDDFTPFFRD
     EKRFWCDTRQ FHELFTQSQI QMMEVSGKYI VRSRTSVVFK EVEQFFARFS YVDVGPTPTQ
     WKESIVIHRG DGKIIRFRLQ PAAHQEWTLW DAQSVHAYTL SAYTARYLFA LISRMQTETG
     MSSLQQFDTE ENLISD