ID   Y880_MYCTU              Reviewed;         143 AA.
AC   P9WMF1; L0T7S8; P67745; Q10542;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator Rv0880;
GN   OrderedLocusNames=Rv0880; ORFNames=MTCY31.08;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP43628.1; -; Genomic_DNA.
DR   PIR; E70780; E70780.
DR   RefSeq; NP_215395.1; NC_000962.3.
DR   RefSeq; WP_003404606.1; NZ_NVQJ01000001.1.
DR   PDB; 4YIF; X-ray; 2.00 A; A/B/C/D/E/F=2-143.
DR   PDBsum; 4YIF; -.
DR   AlphaFoldDB; P9WMF1; -.
DR   SMR; P9WMF1; -.
DR   STRING; 83332.Rv0880; -.
DR   PaxDb; P9WMF1; -.
DR   DNASU; 885205; -.
DR   GeneID; 45424844; -.
DR   GeneID; 885205; -.
DR   KEGG; mtu:Rv0880; -.
DR   TubercuList; Rv0880; -.
DR   eggNOG; COG1846; Bacteria.
DR   OMA; SMTRTVN; -.
DR   PhylomeDB; P9WMF1; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR023187; Tscrpt_reg_MarR-type_CS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS01117; HTH_MARR_1; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..143
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   Rv0880"
FT                   /id="PRO_0000054407"
FT   DOMAIN          5..137
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   HELIX           5..24
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   HELIX           34..46
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   HELIX           51..58
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   HELIX           62..74
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   STRAND          77..79
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   TURN            84..86
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   HELIX           96..117
FT                   /evidence="ECO:0007829|PDB:4YIF"
FT   HELIX           122..138
FT                   /evidence="ECO:0007829|PDB:4YIF"
SQ   SEQUENCE   143 AA;  15576 MW;  F9E2D59CD77E0CE8 CRC64;
     MLDSDARLAS DLSLAVMRLS RQLRFRNPSS PVSLSQLSAL TTLANEGAMT PGALAIRERV
     RPPSMTRVIA SLADMGFVDR APHPIDGRQV LVSVSESGAE LVKAARRARQ EWLAERLATL
     NRSERDILRS AADLMLALVD ESP