ID   Y881_MYCTU              Reviewed;         288 AA.
AC   P9WFY3; L0T6Q0; Q10543;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Uncharacterized tRNA/rRNA methyltransferase Rv0881;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Rv0881; ORFNames=MTCY31.09;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC       superfamily. RNA methyltransferase TrmH family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43629.1; -; Genomic_DNA.
DR   PIR; F70780; F70780.
DR   RefSeq; NP_215396.1; NC_000962.3.
DR   RefSeq; WP_003916735.1; NZ_NVQJ01000001.1.
DR   AlphaFoldDB; P9WFY3; -.
DR   SMR; P9WFY3; -.
DR   STRING; 83332.Rv0881; -.
DR   PaxDb; P9WFY3; -.
DR   DNASU; 885121; -.
DR   GeneID; 885121; -.
DR   KEGG; mtu:Rv0881; -.
DR   TubercuList; Rv0881; -.
DR   eggNOG; COG0566; Bacteria.
DR   OMA; GYHVHRG; -.
DR   PhylomeDB; P9WFY3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..288
FT                   /note="Uncharacterized tRNA/rRNA methyltransferase Rv0881"
FT                   /id="PRO_0000159838"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   288 AA;  30602 MW;  1E360D9E16E9C588 CRC64;
     MTEGRCAQHP DGLDVQDVCD PDDPRLDDFR DLNSIDRRPD LPTGKALVIA EGVLVVQRML
     ASRFTPLALF GTDRRLAELK DDLAGVGAPY YRASADVMAR VIGFHLNRGV LAAAGRVPEP
     SVAQVVAGAR TVAVLEGVND HENLGSIFRN AAGLSVDAVV FGTGCADPLY RRAVRVSMGH
     ALLVPYARAA DWPTELMTLK ESGFRLLAMT PHGNACKLPE AIAAVSHERI ALLVGAEGPG
     LTAAALRISD VRVRIPMSRG TDSLNVATAA ALAFYERTRS GHHIGPGT