ID   Y882_MYCPA              Reviewed;         304 AA.
AC   Q742F3;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_0882c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAP_0882c;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AE016958; AAS03199.1; -; Genomic_DNA.
DR   RefSeq; WP_003872846.1; NC_002944.2.
DR   AlphaFoldDB; Q742F3; -.
DR   SMR; Q742F3; -.
DR   STRING; 262316.MAP_0882c; -.
DR   PRIDE; Q742F3; -.
DR   EnsemblBacteria; AAS03199; AAS03199; MAP_0882c.
DR   KEGG; mpa:MAP_0882c; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; TYPGEHT; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..304
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAP_0882c"
FT                   /id="PRO_0000361192"
FT   BINDING         128
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         157..158
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   304 AA;  32377 MW;  D9EF741591CE7BFF CRC64;
     MTRSEGDTWN LASSVGATAT MVAAARAAAT RRPRPVLTDE YAEPLVRAVG LDVFTKLASG
     ELDPDDLERD VGFARMVDTF AARGRFYDDY FAAAGKAGVR QVVIVASGLD ARPYRLSWPA
     GTTVYEIDQP EVIAFKTATL SRIGAAPTAE LRTIGIDLRQ DWPAALQDAG FDPAQPTAWL
     AEGVLIGFLP PEAEVRLLDS ITPLSAEGSR FAADYGSLND ASQASTEQAR RTTEGWRRRG
     LDMDIAALTY PGKHTDVAAH LGADGWATTT FGLADLFAAA GLPELTEAEQ GPAATLSFVR
     AIKS