ID   Y883_HAEIN              Reviewed;         456 AA.
AC   P44917;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized transporter HI_0883;
GN   OrderedLocusNames=HI_0883;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22541.1; -; Genomic_DNA.
DR   PIR; H64099; H64099.
DR   RefSeq; NP_439044.1; NC_000907.1.
DR   RefSeq; WP_005666065.1; NC_000907.1.
DR   AlphaFoldDB; P44917; -.
DR   SMR; P44917; -.
DR   PRIDE; P44917; -.
DR   EnsemblBacteria; AAC22541; AAC22541; HI_0883.
DR   KEGG; hin:HI_0883; -.
DR   PATRIC; fig|71421.8.peg.925; -.
DR   eggNOG; COG1115; Bacteria.
DR   HOGENOM; CLU_024867_1_2_6; -.
DR   OMA; VSMTQVF; -.
DR   PhylomeDB; P44917; -.
DR   BioCyc; HINF71421:G1GJ1-923-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015655; F:alanine:sodium symporter activity; IEA:InterPro.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   PANTHER; PTHR30330; PTHR30330; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   TIGRFAMs; TIGR00835; agcS; 1.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..456
FT                   /note="Uncharacterized transporter HI_0883"
FT                   /id="PRO_0000161569"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   456 AA;  48827 MW;  69FA3254805DF27A CRC64;
     MTIESILSAI DSFIWGAPLL ILLSGTGLYL TLRLGFIQIR YLPRALGYLF KKDKGGKGDV
     SSFAALCTAL AATIGTGNIV GVATAVQAGG PGAIFWMWLV ALLGMATKYA ECLLAVKYRV
     RDKNGFMAGG PMYYIERGLG IRWLAKLFAL FGVMVAFFGI GTFPQVNAIT HAMQDTFNIP
     VLVTAIIVTL LVGLIILGGV KRIATASSVI VPFMAILYVT TSLVIILLNI EKVPDAILLI
     IDSAFDPQAA LGGAVGLTVM KAIQSGVARG IFSNESGLGS APIAAAAAQT REPVRQGLIS
     MTGTFLDTII VCTMTGIVLV LTGAWNNPEL AGATVTNYAF AQGLGTSIGA TIVTVGLLFF
     AFTTILGWCY YGERCFVYLV GIRGVKLYRL AYIMLVGLGA FLHLNLIWII ADIVNGLMAF
     PNLIALIGLR KVIIEETKDY FQRLKINHYD QDEVIK