ID   Y8886_DICDI             Reviewed;         722 AA.
AC   Q54IG2;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Heat shock protein DDB_G0288861;
GN   ORFNames=DDB_G0288861;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; AAFI02000125; EAL63052.1; -; Genomic_DNA.
DR   RefSeq; XP_636515.1; XM_631423.1.
DR   AlphaFoldDB; Q54IG2; -.
DR   SMR; Q54IG2; -.
DR   PaxDb; Q54IG2; -.
DR   PRIDE; Q54IG2; -.
DR   EnsemblProtists; EAL63052; EAL63052; DDB_G0288861.
DR   GeneID; 8626800; -.
DR   KEGG; ddi:DDB_G0288861; -.
DR   dictyBase; DDB_G0288861; hsp83.
DR   HOGENOM; CLU_383312_0_0_1; -.
DR   InParanoid; Q54IG2; -.
DR   PRO; PR:Q54IG2; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Stress response.
FT   CHAIN           1..722
FT                   /note="Heat shock protein DDB_G0288861"
FT                   /id="PRO_0000363912"
FT   DOMAIN          40..179
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT   REGION          99..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..529
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        554..575
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        576..666
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   722 AA;  82547 MW;  F193B0F113C1C565 CRC64;
     MATIMDFLLR QGLNVPVGYS SVGSQSTSSS STSIPMDSSL RNVDYLPEID ITETKDSLII
     ECELAGVLKE DISIEVAESK LIIKGDKKRY AYRRPNQSWS YDDKNQISQS SKISEQSSGA
     DQWQHSNDPN VDSQSNLNMP SSKQDPNVQQ SRVGNVPESK VNRNDTTEPN LPSQPFQSDM
     NPSSSSSSIE KQQIPNVSHP SFQQWSGQPQ PQQQQQQQQQ QQQQQQQQQQ QQQQPFEQQS
     QQQSNLNDPM QRQDSKEISQ PSELQRSNFG ESSVNQPSSS SSSLLGSDNS QSNVDLPSSR
     SVEPQRPNVS DSDTNQGYSQ SVEQRLGNTQ QQSSQLPQQQ QQQQDQPRSN VNEPSFQQWS
     SQQDQHRSNV NDPSSQQWSS QPSEQQQKSN ISESNVSQPS STQFVENIPS NLEQLPQQEQ
     QRSNGNEPSS QPWSSQPSEQ QRSNINEPPS QQWSSKQDQQ RSNVNDPSSQ QWSSRPSEQQ
     QQQQKPNIGE LNVNQASSDV CSGPSVSETR KQFEENYLNE QQRQPQQQDL SSLHKDEKKP
     SSSSVSQTAQ LFEPNKREEQ RKDKPEEKKF DSDIIKSSEP TNVESIENKD WIQQKPQEQQ
     QEPREISSTE TSNLQQPMER QINTETPKEQ QVSPQQQQPQ QQQQPQQQQQ PQQQQPQPQQ
     QQQERKYISE RTFGHFKRTM DLSKMLYRLN LREEVQTHFV NGLLIIILNK KPFEPSIKIP
     VN