ID   Y888_HELPY              Reviewed;         255 AA.
AC   O05732;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Probable iron chelatin transport ATP-binding protein HP_0888;
GN   OrderedLocusNames=HP_0888;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49503 / 60190;
RX   PubMed=9139899; DOI=10.1128/jb.179.9.2852-2856.1997;
RA   Cao P., Cover T.L.;
RT   "High-level genetic diversity in the vapD chromosomal region of
RT   Helicobacter pylori.";
RL   J. Bacteriol. 179:2852-2856(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Part of a binding-protein-dependent transport system for an
CC       iron chelatin. Probably responsible for energy coupling to the
CC       transport system (Potential). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; U94318; AAC45245.1; -; Genomic_DNA.
DR   EMBL; AE000511; AAD07936.1; -; Genomic_DNA.
DR   PIR; H64630; H64630.
DR   RefSeq; NP_207681.1; NC_000915.1.
DR   RefSeq; WP_000242349.1; NC_018939.1.
DR   AlphaFoldDB; O05732; -.
DR   SMR; O05732; -.
DR   STRING; 85962.C694_04560; -.
DR   PaxDb; O05732; -.
DR   EnsemblBacteria; AAD07936; AAD07936; HP_0888.
DR   KEGG; hpy:HP_0888; -.
DR   PATRIC; fig|85962.47.peg.946; -.
DR   eggNOG; COG1120; Bacteria.
DR   OMA; VRQADRY; -.
DR   PhylomeDB; O05732; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Iron;
KW   Iron transport; Membrane; Nucleotide-binding; Reference proteome;
KW   Transport.
FT   CHAIN           1..255
FT                   /note="Probable iron chelatin transport ATP-binding protein
FT                   HP_0888"
FT                   /id="PRO_0000093210"
FT   DOMAIN          3..240
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         35..42
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   255 AA;  28682 MW;  84BE756D3332BC3A CRC64;
     MVLEVKNLSF KYSQKLILDK LSFSVPKNSI TSILAPNGSG KTTLLKCLLG LLKPLEETEI
     KACNKDILPL KPYEKAKLIA YIPQVEYYAF NFSVLDFVLM GKATHLNLFA MPKAKHIKEA
     TSVLERLDLE SLKDQGINDL SGGQRQMVLL ARSLLQRTPL LLLDEPTSAL DLKNQALFFD
     AIKDEMKKRE LSVLVNIHDP NLVARHSTHV VMLKDKKLFL QASTPIAMTS HNLSALYDTP
     LEAIWHDNKL VVYAL