ID   Y889_HELPY              Reviewed;         326 AA.
AC   O05731;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=Probable iron chelatin transport system permease protein HP_0889;
GN   OrderedLocusNames=HP_0889;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49503 / 60190;
RX   PubMed=9139899; DOI=10.1128/jb.179.9.2852-2856.1997;
RA   Cao P., Cover T.L.;
RT   "High-level genetic diversity in the vapD chromosomal region of
RT   Helicobacter pylori.";
RL   J. Bacteriol. 179:2852-2856(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Part of a binding-protein-dependent transport system for an
CC       iron chelatin; probably responsible for the translocation of the
CC       substrate across the membrane. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. FecCD subfamily. {ECO:0000305}.
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DR   EMBL; U94318; AAC45244.1; -; Genomic_DNA.
DR   EMBL; AE000511; AAD07937.1; -; Genomic_DNA.
DR   PIR; A64631; A64631.
DR   RefSeq; NP_207682.1; NC_000915.1.
DR   RefSeq; WP_000921458.1; NC_018939.1.
DR   AlphaFoldDB; O05731; -.
DR   SMR; O05731; -.
DR   DIP; DIP-3475N; -.
DR   IntAct; O05731; 3.
DR   MINT; O05731; -.
DR   STRING; 85962.C694_04565; -.
DR   PaxDb; O05731; -.
DR   EnsemblBacteria; AAD07937; AAD07937; HP_0889.
DR   KEGG; hpy:HP_0889; -.
DR   PATRIC; fig|85962.47.peg.947; -.
DR   eggNOG; COG0609; Bacteria.
DR   OMA; HIVWLIR; -.
DR   PhylomeDB; O05731; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0033214; P:siderophore-dependent iron import into cell; IBA:GO_Central.
DR   Gene3D; 1.10.3470.10; -; 1.
DR   InterPro; IPR037294; ABC_BtuC-like.
DR   InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR   PANTHER; PTHR30472; PTHR30472; 1.
DR   Pfam; PF01032; FecCD; 1.
DR   SUPFAM; SSF81345; SSF81345; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Iron; Iron transport;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..326
FT                   /note="Probable iron chelatin transport system permease
FT                   protein HP_0889"
FT                   /id="PRO_0000060283"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   326 AA;  34624 MW;  128BCB142D429D1C CRC64;
     MLKTYHIALA CVILAVVVLL FGGESLSLEE WQEVCLNVKN HFLHNEELSS LSIIILEIRL
     PRVILALLVG ASLSGSGVVM QTIFRNPLVD PFLLGISSGA MLGVAMAIAV VESNIAILAF
     FGAILASLAV LAMNRVLGNS VLSLVLSGVV LSAFLSALAG AIKFFVIPQK AQAIVVWLLG
     SLSLSSYKDC LIAFIGLSLG FIPLFLLRWR INLLSLSDAQ SLSLGINPVL LRSLCLVCVS
     VASALAVSVS GTIGWIGLVI PHVARLFFGA NLQKLLLSSL LMGAFFLLLA DVVAKTITPY
     DLPVGIATSV LGAPFFLWLL FRTRGV