ID   Y890_MYCTO              Reviewed;         882 AA.
AC   P9WMG0; L0T7T8; Q10550;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Putative HTH-type transcriptional regulator MT0914;
GN   OrderedLocusNames=MT0914;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
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DR   EMBL; AE000516; AAK45159.1; -; Genomic_DNA.
DR   PIR; G70781; G70781.
DR   RefSeq; WP_003900227.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMG0; -.
DR   SMR; P9WMG0; -.
DR   PRIDE; P9WMG0; -.
DR   EnsemblBacteria; AAK45159; AAK45159; MT0914.
DR   KEGG; mtc:MT0914; -.
DR   PATRIC; fig|83331.31.peg.982; -.
DR   HOGENOM; CLU_004665_5_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..882
FT                   /note="Putative HTH-type transcriptional regulator MT0914"
FT                   /id="PRO_0000427310"
FT   DOMAIN          814..879
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        838..857
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   882 AA;  94470 MW;  69415B40F10BD425 CRC64;
     MRALLAQNRL VTLCGTGGVG KTRLAIQIAS ASELRDGLCF VDLAPITESG IVAATAARAV
     GLPDQPGRST MDSLRRFIGN RRMLMVLDNC EHLLDACAAL VVELLGACPE LTILATSREP
     IGMAGEITWR VPSMSITDEA VELFADRASR VQPGFTIANH NAAAVGEICR RLDGIPLAIE
     FAAARVRSMS PLEIADGLDD CFRLLAGGVR GAVQRQQTLR ASIDWSHALL TETEQILFRR
     LAPFVGGFDL AAVRAVAAGS DLDPFSVLDQ LTLLVDKSLV VADDCQGRTR YRLLETVRRY
     ALEKLGDSGE ADVHARHRDY YTALAASLNT PADNDHQRLV ARAETEIDNL RAAFAWSREN
     GHITEALQLA SSLQPIWFGR AHLREGLSWF NSILEDQRFH RLAVSTAVRA RALADKAMLS
     TWLATSPVGA TDIIAPAQQA LAMAREVGDP AALVRALTAC GCSSGYNAEA AAPYFAEATD
     LARAIDDKWT LCQILYWRGV GTCISGDPNA LRAAAEECRD LADTIGDRFV SRHCSLWLSL
     AQMWAGNLTE ALELSREITA EAEASNDVPT KVLGLYTQAQ VLAYCGASAA HAIAGACIAA
     ATELGGVYQG IGYAAMTYAA LAAGDVTAAL EASDAARPIL RAQPDQVTMH QVLMAQLALA
     GGDAIAARQF ANDAVDATNG WHRMVALTIR ARVATARGEP ELARDDAHAA LACGAELHIY
     QGMPDAMELL AGLAGEVGSH SEGVRLLGAA AALRQQTRQV RFKIWDAGYQ ASVTALREAM
     GDEDFDRAWA EGAALSTDEA IAYAQRGRGE RKRPARGWGS LTPTERDVVR LVSEGLSNKD
     IAKRLFVSPR TVQTHLTHVY AKLGLASRVQ LVDEAARRGS PS