Y8923_DICDI
ID Y8923_DICDI Reviewed; 5801 AA.
AC Q54FZ8; Q54FZ7;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 2.
DT 23-FEB-2022, entry version 68.
DE RecName: Full=Putative uncharacterized transmembrane protein DDB_G0290641;
GN ORFNames=DDB_G0290641;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SEQUENCE CAUTION:
CC Sequence=EAL62118.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAL62181.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AAFI02000164; EAL62118.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AAFI02000164; EAL62181.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_635619.1; XM_630527.1.
DR RefSeq; XP_635620.1; XM_630528.1.
DR STRING; 44689.DDB0216167; -.
DR PaxDb; Q54FZ8; -.
DR PRIDE; Q54FZ8; -.
DR EnsemblProtists; EAL62118; EAL62118; DDB_G0290515.
DR EnsemblProtists; EAL62181; EAL62181; DDB_G0290641.
DR GeneID; 8627691; -.
DR GeneID; 8627692; -.
DR KEGG; ddi:DDB_G0290515; -.
DR KEGG; ddi:DDB_G0290641; -.
DR dictyBase; DDB_G0290641; -.
DR eggNOG; ENOG502RSR9; Eukaryota.
DR InParanoid; Q54FZ8; -.
DR PhylomeDB; Q54FZ8; -.
DR Reactome; R-DDI-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR PRO; PR:Q54FZ8; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031248; RNF213.
DR PANTHER; PTHR22605; PTHR22605; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..5801
FT /note="Putative uncharacterized transmembrane protein
FT DDB_G0290641"
FT /id="PRO_0000346913"
FT REGION 1114..1136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1827..1846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2040..2109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3351..3392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5134..5168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5478..5573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5600..5638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1115..1136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2041..2109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5134..5156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5496..5573
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5600..5623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5624..5638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5801 AA; 671588 MW; E71E2B2707C5C31F CRC64;
MLTHDLTKNL GRPSFLPKEL TISDSQVQRL KTPCFEEIIR SFLNKRKPKQ NWQLSLEIEE
KLSNPTILDI FKTIRTTEET IISDESSRDF FIYSLLKIDC CIKGNLFSYY SEMDRTNIKD
IIIGKGLKNN NNNIILGNSI FFKKIVEDFL TMAFERFSWY CENKSTDLLF FICVMSESNE
RLKEFFNKFQ DYHHHHNQSK TAEHYKISKS LNSLPFSISN GVISNGVNPT IKIQWFLKFV
ELNLKNPIVY QLFDYTIINY PFISNLNILV GPILLNIFNN DNIKIYEDNN NNNNNNNNNN
NNNNNNNSTI VDKFNLTLEL KSKLAFSVYK RKLAICAVTL PILVLHLQKD PIGFLKYYDE
FIKSSPESKS LFNHSISLHL SNDTKKMFNL LPYRNRIDLG WESFIVNKLT TADKINILST
YDETYQDVKA IIICSLNVES YALLSLESKL SDQFLINVFN QQCRLPNNYN FSGVITSFST
IEREYVSRLK NSIEQEAIKK KQLIVKQIEM NSEIYENYFR IVNVMVEALL NQNPSLNSII
ECVGTDLGGS LEQDNQYMDT LPNLVLFSHL LRRIATSNLN SSYLLKKDSK GNNRLNLDLS
NLAMFYNSKN SFWQEIRGPY DSFLREFIKN LLAKYVEIKS DFKYLDYHYF ESLTIILLEM
KRRYNCIPSD YRVSNKPVKI VEFKDFIKKF EEKESQYNDL LLVKEYLERK FSFNFSSQFD
KNWKTSKRLK LLRQLIKSTK SLYGHYIQDD ESIKFLLHFA IVNKTLFFHA IFDYYYLNSS
DQTNSKQLNL DQCLKSTREF LKRLIESDSS IQLNDIFKKI TEITDINYVR EIEPIYNYFK
GNGEPYKKEL EEQIQKFIDN ATFFFGVRKY LPHIEKFIES LDFIVITDFN KKKAKCEEII
KSVFEKNTTI AGANDALILL KSIMKDINFI QLPFFSLNIK DIIEWFSSFT DFKNFNIQVE
IASNNYNDSY SAQILDYTLF CRNQFTELVQ YSIDSTKDEK PKQMEFSKFF ELINQIIPVS
GYLSAVNKIS SAINNLSNVK VLFKSGNFNE QGTLQNAEMA TNSKSKFTSE TYNTNNNSTN
GSNWWVVSEN GFELAQDKLE NSYRGIDIFS KFDDDDNNNS NNNNNNNNNN NNNKKIIDNK
KTFDTFRIIF KLFKKIHSLH NELYKICHPK FMALQSIQVA CDLETLKKEK RHLRNSIKVW
KDFISSLPKN LLFLRAPGVS SLYSKLKLTF ENKFNNNNNN NNNNIQQQQQ QFDLFLNDLV
LDLFPSIKYC FYEYPQIINM KLLKNQIEST TNQLLNEKTN SKILIDDEIV SGCFIEKFLK
ELIRNIKQNL LYIEDDEEEV EEEVGGVEIG QLKNQPIGVP PPNVNKFDLI NSFELVNIEC
NDDLFNSLME LNDSQLPHPS QIFYANSFDA DFPFFKCLVE KFSESIFFLI GTPNKKDEFI
NWMSVHFSNN TMSKLAKVYV ISIGDDTHTK DVFSFLSPYS GKNNNIGNTN NSWESFKVLW
NKTKVQNGIE SLNLVSGGTG TGKSHFIKSE IKAKNGGGGG RNLEIEKPNE HTVLVRPGFI
IDPLIKKIKA LKDATNFFIH FNISCYADFQ EFSQFFYPLI SFGYIFGKQD GELCSIPTGC
LLTIYVELGD PLGSDYRKNE NNTIQSIEYL KYVKTSIPLI FHLSDTEMSK KYLLAEWVSG
EAEWRAFAFS SDHCSFYQKA TVEMGKDVKL SQYLDYINQM FKRNFPTIDI NYLFDKTKYP
FRKNFFLMLN ERLKFLETYY EFYLVICDHD FQNSNTVLQD SLLTYQELYE VFLVECAQLA
NPEFSQQKTI WEKPPLITNR SVVKVTKDRS SSSSSSYSGG GSSINNDNIS SKQVDFIDLS
NNNGLTKSGS KISNYNNQID RLIESKIKKL PTYITLDKAN ENIRLFNTKI ASSFGIQSRT
NIVTDLANQY GFVLTPELSL RLFILNNRIQ HHRSMVLTGD TGVGKTMLLI FYSLLINAGL
NAIPDIIFEI KEVIIKFART LEGFSFSQEI VNLNVDFSID KILLASKEIF NFVPKHLKEN
NGENNPVQQL QQQNDGDKQQ NPQQPQQQQQ QQQQQQQQQQ QQQQQQQQPK QQQQQQLKHK
NSETSSPLFK HQTSFIKEVE EIIVKIVEAY QLIDISRSPS IQDIMKKKRT SPIATYLNNN
KTVKLDSLLE QLKEICTIPF KRLFTRIIMN KKISGKDFKA IVNTIIKESN ELKKIDQDLK
MVVFIDEYNT SCEESLSLIN EIFVDGTFDG EYCLPDNIFW IGAMNPLVET VGNAINYTGE
SLSSSSSGNN LFSSSSSITS SSTDITTSNN YEFVVQETPP PLKQLELDYG SLSVSNESSF
CASLIRLNES GIIPAYLNVD LDYPNQVGID INQMIIIGQK CLRKEKQART HVSFRDIIRA
IDLYQFFVQE IGVEILKTIN ENENEKISPI QTHWLALICS VSMTYIHRLN PDNRSKMVNA
FNEYIGKFSG NNLNSFKKSS SSSNNNNGDY VTEIFKSIIC GVSKQTTIPN GVARTESLQL
NIFFTLVSIY TCIPICIVGP PGCSKTLSFS IVNDNLNSHG PTSNRPKLYS FLKSTQPFRY
QCNNHTSDTE IKEVLDKAIR RGDIITDRVR MVVHLDEAGL VNENTSPMKI MHDYLDKGTR
SKTLITIIIL SNKILDAAKT NRMLLLVHPK EVSIQDQHSL VKGCLFGRID KLTDYEENIC
TALCNAFSEI NTHDSSSLQD IDNSNINNIN KNNGNTISDI SDIHPKLNKR IFAQRDFVFF
LRHLRRAFEI KGKLTPEDLL VSLERNFIGT KIFKPHLQSF FKHLGFESDQ LLAHDNTIVR
IKQSLQDKLD INTDINSQGF RYMMLLDPTD SETSLLILKE IGVEHTVIRV GDFENDQTTE
SLSHTVSEIK IKMSQGGTVV LVNSQSIQAC FYDVFNRYFT IYQQDDEKSF LAHLSFGINS
MFCPVHPDFR VIVHLPLSRL NVTQYPWLNR FEKYILSMDQ LLSYSLSKAS LENIQNYHDH
QSNTKAFFKN LLVSAQDFVD EIHIGKLNGS LLFGYTKSTI QSLVYQAFKD NSNFSPYSIS
KEDLKKMSLL PPDQQINPST LLNLKLLQIA RPESLYKCTK SLPKSYVEQY LSNQEHFNVY
LFLKNLVESF SKNQNQQQQQ QQQQELEVDS EQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
QQQQQQQQQQ QSKWMVFTRT SFSLHSIRDS DKNDKFLLLL ESNIKVNRNG GSKNLFKVLQ
LHTFKSKVKC SKEIIDFCTS EEQMVIIIIA DMLVVTNNQI NFVHEVFDQH ANRANKLLVF
ISHFPPEFSI SSQNNINSIF LNNTEYIYID SLGIKIDNSL ISDSGIKSDL EKSNNNNNNN
NNDNSGNNSG NEIDGSSNGD NNNNNNNNNN SGEMKFDIRG WISKVYGITD NKPLDETTFL
ESMFFKYLYQ ISSSMANSQL MGYIEPKELR VEESQFYSNA TKRVEYIKTI FENNNSWVKC
IIDQFLKTWN GTNLITNIIA DVSSDIVSTK STQSFFESII SSIKSFFYPV ISQIIKHLIN
HYSFLSIYEV KPNSMEQKMV EKFIISANSL KISDSVEERF EPIRILPPII RKVRSELLLY
DSISTVINQL FDQALSTCKF MSNYGFLYKE FYQLVSKHPI KPLLDYIVSE EPLLERFNND
FIIRTLKFEK TVSKFFFNLI DSFKGRFVTS SSSPSSSSKK DNINSHPILE LWVTSHFEHR
TLFYLKNILL PIINLKGVDL ISELLKIPLN NNINRTIEDY KRLIVDFSFN LLYNRLLVLL
DQVKCNDSYN EDIFLNWISV VREVLNISKT ISNVLKDLRK ISNGSNNDDS YLKAIQVFIS
YSILMDSCIN SINFIKNEDG TISTTPKNTT KSSSPSVSTL HSMVKIYYNF FNKEFKSDSF
NVLFNNLIEF KKEKESKLIG DSYSSILQKT CLLDILDPIA TLSRENFSQF LRVLQDPKRN
NKIEIPIGWI CSVIGEYINL EDNYQFLREK VNEICCKSCE EYYFPPLVSK PTGLSFKFLG
ITEKSYIHSF KLLEDSIYYA ELNRIKSEEL NSLCSSHLRE KFLREPFSNI ILESINTQII
EKFADLLNSN IENAKEVLEK TKILKGTLQS ILVAPENPNG KILKLINFYH MTLINHLKES
TMATLLRDEA FLSTFGLRLH LLDSDKISGV DASQRGVNLS NKTEVDFSQL RFIYDSSNNS
YGVLFKKIEQ LINSSDKPEF EKLTETLNTP DCQGLFRASL FIILYQYYLD GLDCSAFKYL
FESKEQDSTR KFFDLQNFTE YYLPFIYPDQ KLNKNIGVHK LLMRQENKER EDITAAQITI
NSIAISIGSN SNTFLYNLTR HIQTVAGQYF PACDVGNIFR DCAMIYLDGQ DDHTVTMGYD
VLYKYIVSCC SWSAFTFTVS VQPRYTEYLL KPQIHFVSKL DKKDHVSLTN YLWNRALTSI
NEIIRNPELS SSLIEPSQYI SEFLYQIWLD GHTLNNSQQT QHFRSHFANT TQVTNYEKYL
CNVLTKIKKE NESRKSHLMR IFAQRTIVSS KNKEIQMNIN SIRSDFVRSY ERPYFTFEKI
NQFCSSSNGS SKNFEVLTFM SNQIQKICLS KHFTPLVNFI VLFHQFLKFR LQENQFNFNF
NQCVQILLDK QYETEESIKP LRLAWTHFTN AWKSVIKEMN IIEGGCAQKP EYEKVAFPIH
DETPMSVILF DSDSNGSGVI LNLINGWVSH TQSPCLNLRN DVPMSPLFKT IAEGFIPKGV
TYDISDLPEG ENYLLLGSDF EPNDYHQFIY RLFSQYQTFD KETMSPDFLS IQNRVINRFF
AGKGVAGILE NYSKRFPFQK VISEQDSVVK KKLASLLLDD EIQSLSNLVR NLYSLIQKLP
EIYFKDIGHS YLKIHFENTL SARQNYLDDF SQELSTLVSN IINLTNEQQS IDVNQSIFHF
RNSITTFVPL DLAKQLSINM VGTISIMLIN SSLKQKKLYR NFCPEPKIID GKYIEFFDRF
KSNIIEKAKN EADNLNFLRN LCEYIREVHS KLVSNDVLKE ISVSTSESIT LAQIIQKRIP
EFSFDKEVIS KKSFCLNGTP TSYYRILIKT ITDIYNHINP MIQNKKNTVY SEIFTNHFNS
INSEEEIKQI NIDSIRTSNN SSPNLIQKIN EQLDNNNNNN NNNNNNNNNN NNNIDHGDDN
NDGESESDIE DYENINSTCG KIKIIKNTTR KIDQIDNHPF KHYLYYWIRY LSQFCELLNV
EPLNNYNNNN NDFKIFSLFK LFKLQSFEQN YDQNSPIIIN RLDKKLSKGL ITSISPMETM
IHILNRLSKL DSNIKQLFNW KFKIICDECK ENTESSGFIK LTLDLTNINE TNRSIKSLLM
STLLYSIKIR NCNHNKSDIK LVESPEYIFI EVERFKKGLP FNSSIINFEK NISISELLGN
FSKDINGLYN IQSILSYGSR NDEFDFITSN EGQYYHLTSS SCVKTLNEYS FNAIIESLNN
NCNFIILKKG GYIKTSHISD PVDPSLLNKP PIPSSDNEEE EEDDDDDEVN EDEYENGNED
EDEDEDEDED EDEDEDEDED EDEDEDEDED EDEDEDEDED EEYEDEDEDE DIIGDDAEVE
KENKNGFSHL ESLQITPIPH DKDEEQPEKP QQQEIHQQPE KPQQPEKPQE LQSTETPGQE
VSVDYKILYD RKAFKEFLYG GFEKFTEDLK LQILDAGINC FSVLLNLKSE DWSKFSFLQL
PKRNQLVNSY KKIHNEAIKK EYPFESPFDI DDQKAYEQFL KDIVNDEKTI MDLVEAGFDS
FTSLIPSDDG GWEEVSLNLQ EILKPATCFN LINQLKLVGK A
