ID   Y892_MYCTO              Reviewed;         495 AA.
AC   P9WNG0; L0T532; P64745; Q10532;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Uncharacterized monooxygenase MT0916;
DE            EC=1.14.13.-;
GN   OrderedLocusNames=MT0916;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the FAD-binding monooxygenase family.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK45162.1; -; Genomic_DNA.
DR   PIR; A70782; A70782.
DR   RefSeq; WP_003404651.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WNG0; -.
DR   SMR; P9WNG0; -.
DR   EnsemblBacteria; AAK45162; AAK45162; MT0916.
DR   GeneID; 45424855; -.
DR   KEGG; mtc:MT0916; -.
DR   PATRIC; fig|83331.31.peg.984; -.
DR   HOGENOM; CLU_006937_7_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   Gene3D; 3.50.50.60; -; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR020946; Flavin_mOase-like.
DR   Pfam; PF00743; FMO-like; 1.
DR   SUPFAM; SSF51905; SSF51905; 2.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Monooxygenase; NADP; Oxidoreductase.
FT   CHAIN           1..495
FT                   /note="Uncharacterized monooxygenase MT0916"
FT                   /id="PRO_0000427133"
FT   BINDING         16
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000250"
FT   BINDING         36
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000250"
FT   BINDING         45
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000250"
FT   BINDING         56
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000250"
FT   BINDING         62
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000250"
FT   BINDING         105
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000250"
FT   SITE            286
FT                   /note="Transition state stabilizer"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   495 AA;  55039 MW;  08CB55F48674DB44 CRC64;
     MTGRCPTVAV VGAGMSGMCV AITLLSAGIT DVCIYEKADD VGGTWRDNTY PGLTCDVPSR
     LYQYSFAKNP NWTQMFSRGG EIQDYLRGIA ERYGLRHRIR FGATVVSARF DDGRWVLRTD
     SGTESTVDFL ISATGVLHHP RIPPIAGLDD FRGTVFHSAR WDHTVPLLGR RIAVIGTGST
     GVQLVCGLAG VAGKVTMFQR TAQWVLPWPN PRYSKLARVF HRAFPCLGSL AYKAYSLSFE
     TFAVALSNPG LHRKLVGAVC RASLRRVRDP RLRRALTPDY EPMCKRLVMS GGFYRAIQRD
     DVELVTAGID HVEHRGIVTD DGVLHEVDVI VLATGFDSHA FFRPMQLTGR DGIRIDDVWQ
     DGPHAHQTVA IPGFPNFFMM LGPHSPVGNF PLTAVAESQA EHIVQWIKRW RHGEFDTMEP
     KSAATEAYNT VLRAAMPNTV WTTGCDSWYL NKDGIPEVWP FAPAKHRAML ANLHPEEYDL
     RRYAAVRATS RPQSA