ID   Y8960_DICDI             Reviewed;         145 AA.
AC   Q54H97;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=CBS domain-containing protein DDB_G0289609;
GN   ORFNames=DDB_G0289609;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA   Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA   Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT   "Changing patterns of gene expression in Dictyostelium prestalk cell
RT   subtypes recognized by in situ hybridization with genes from microarray
RT   analyses.";
RL   Eukaryot. Cell 2:627-637(2003).
CC   -!- DEVELOPMENTAL STAGE: Expressed in PstA and PstO cells in the slug
CC       stage, becoming preferentially restricted to PstO cells during
CC       culmination. {ECO:0000269|PubMed:12796308}.
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DR   EMBL; AAFI02000147; EAL62622.1; -; Genomic_DNA.
DR   RefSeq; XP_636127.1; XM_631035.1.
DR   AlphaFoldDB; Q54H97; -.
DR   SMR; Q54H97; -.
DR   STRING; 44689.DDB0230005; -.
DR   PaxDb; Q54H97; -.
DR   EnsemblProtists; EAL62622; EAL62622; DDB_G0289609.
DR   GeneID; 8627230; -.
DR   KEGG; ddi:DDB_G0289609; -.
DR   dictyBase; DDB_G0289609; -.
DR   eggNOG; ENOG502SC5H; Eukaryota.
DR   HOGENOM; CLU_1565764_0_0_1; -.
DR   InParanoid; Q54H97; -.
DR   OMA; MERDIFV; -.
DR   PhylomeDB; Q54H97; -.
DR   PRO; PR:Q54H97; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   Gene3D; 3.10.580.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   Pfam; PF00571; CBS; 2.
DR   SMART; SM00116; CBS; 2.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   2: Evidence at transcript level;
KW   CBS domain; Reference proteome; Repeat.
FT   CHAIN           1..145
FT                   /note="CBS domain-containing protein DDB_G0289609"
FT                   /id="PRO_0000392670"
FT   DOMAIN          9..66
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          84..141
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   145 AA;  16104 MW;  30F3A41135EE31E7 CRC64;
     MKVLVKQLMS KSLFTINLDT TLDVALKSLN ANSIHRLPVV DNDGNLKGII TDRDLRLATD
     SPFLPENNED RLEKLRLHKV SSIMKQNPVT IEDFSPVVEA AKLMRVTNVG GLPVLDKKGR
     LIGMVTRSDL LDLLIKVLEP VPPQS