ID   Y899_CHLAA              Reviewed;         597 AA.
AC   Q45827; A9WH37;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Uncharacterized sensor-like histidine kinase Caur_0899;
DE            EC=2.7.13.-;
GN   OrderedLocusNames=Caur_0899;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-18.
RX   PubMed=8661927; DOI=10.1007/s002030050337;
RA   Synstad B., Emmerhoff O., Sirevag R.;
RT   "Malate dehydrogenase from the green gliding bacterium Chloroflexus
RT   aurantiacus is phylogenetically related to lactic dehydrogenases.";
RL   Arch. Microbiol. 165:346-353(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; CP000909; ABY34132.1; -; Genomic_DNA.
DR   EMBL; X89038; CAA61437.1; -; Genomic_DNA.
DR   RefSeq; WP_012256788.1; NC_010175.1.
DR   RefSeq; YP_001634521.1; NC_010175.1.
DR   AlphaFoldDB; Q45827; -.
DR   SMR; Q45827; -.
DR   STRING; 324602.Caur_0899; -.
DR   EnsemblBacteria; ABY34132; ABY34132; Caur_0899.
DR   KEGG; cau:Caur_0899; -.
DR   PATRIC; fig|324602.8.peg.1030; -.
DR   eggNOG; COG4585; Bacteria.
DR   HOGENOM; CLU_466746_0_0_0; -.
DR   InParanoid; Q45827; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   Pfam; PF13492; GAF_3; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Cell membrane; Kinase; Membrane; Reference proteome; Transferase;
KW   Transmembrane; Transmembrane helix; Two-component regulatory system.
FT   CHAIN           1..597
FT                   /note="Uncharacterized sensor-like histidine kinase
FT                   Caur_0899"
FT                   /id="PRO_0000066304"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          393..597
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT   CONFLICT        13
FT                   /note="S -> L (in Ref. 2; CAA61437)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   597 AA;  66021 MW;  699E22D18A60D131 CRC64;
     MTSPAKSSTA ASSSSQRSLS AWSPLGGERF YAAARWVLII LLGVVTQFLT NGGLWPVTDE
     IGPLEGIFWL YVGFALVFTV LAFLQFAAGL VSISYLFDIA FISLMTFFGG ERIVIFFPLY
     LVPLTYAAIR QSRSVSLLSG LLAAVAYMAA FIAWRRLIAP EALMTLLDYV ALALRGTTLA
     IVPWVTGNLA ERQSEFNRER VTQAQRDAEQ ALSEARAYRD QMRSLYRVAL TLGSTANYRQ
     VLDTLLQESQ KIVPYRAGIV LLSSGQPNEL YVAFGSNLAP GDLNRSLKMD TGLAAALRAN
     TAQVITSFTQ FPSLQQLGSL RTCKAAALLP LQAGMRVYGL FVVATDQTLT TDQVEMLMAL
     ANYAIVALHN AQLIYDLKEE REKLLSHEEE VRHQLARDLH DGPAQAMAVI TMKAEFIKRL
     LERDPAQALA ELDELSSIAK RTNYEVRTML FELRPLMLET QGLKVTLEQY LDRLRAKAGN
     TAIVLEGTDI DKVRLGSKVE GALFNMIQES VTNAIKHAKA NHIWVRLRRL NDQMLEVVIQ
     DDGVGFDKAA VLKSYERRGS FGLLNIDERA RLVGGRAEID STPGKGTQIT IFVPIES