Y9144_DICDI
ID Y9144_DICDI Reviewed; 1123 AA.
AC Q86K40; Q54ZV2;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Putative uncharacterized protein DDB_G0277255;
GN ORFNames=DDB_G0277255;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000019; EAL68813.1; -; Genomic_DNA.
DR RefSeq; XP_642764.1; XM_637672.1.
DR AlphaFoldDB; Q86K40; -.
DR PaxDb; Q86K40; -.
DR EnsemblProtists; EAL68813; EAL68813; DDB_G0277255.
DR GeneID; 8620953; -.
DR KEGG; ddi:DDB_G0277255; -.
DR dictyBase; DDB_G0277255; -.
DR eggNOG; ENOG502RCF0; Eukaryota.
DR HOGENOM; CLU_280119_0_0_1; -.
DR InParanoid; Q86K40; -.
DR OMA; SILTHGH; -.
DR Reactome; R-DDI-1299308; Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK).
DR Reactome; R-DDI-1299316; TWIK-releated acid-sensitive K+ channel (TASK).
DR Reactome; R-DDI-1299344; TWIK-related spinal cord K+ channel (TRESK).
DR Reactome; R-DDI-1299361; TWIK-related alkaline pH activated K+ channel (TALK).
DR Reactome; R-DDI-1299503; TWIK related potassium channel (TREK).
DR Reactome; R-DDI-5576886; Phase 4 - resting membrane potential.
DR PRO; PR:Q86K40; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015271; F:outward rectifier potassium channel activity; IBA:GO_Central.
DR GO; GO:0022841; F:potassium ion leak channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0030322; P:stabilization of membrane potential; IBA:GO_Central.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..1123
FT /note="Putative uncharacterized protein DDB_G0277255"
FT /id="PRO_0000348176"
FT REGION 136..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..1005
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1070..1099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..984
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1123 AA; 121119 MW; A9B0ADEA9569615C CRC64;
MTTILKGYYL KVTLENRIVK HNGRKVYLSI VEHGNGIPDH ALILKTTAKC VKFSVCLSIR
SQCGWKELDQ NDSGELTFDL KVEVTGKSQR APLFPLIFQL CEKNYDQVTL ISKSVIPVKA
ITKIPKKSLR AELVPLGESP TKPPQAFPAS PSDLISSKEY DDEFDGGNGG NSGTNGDGDD
GGCSLGGLAD ENDYEDGMVI DENGNVCSSG SGDGGGGGGG GGDISPKLTS SLNNLKSSIS
NTSLSSLGNS LNNSLNGTNS QMLQYQQQQQ QQQQQHGNLN VSGNNINNNR DTNVSGNNNN
NNNSTTTTTT TTTTTTHSNN SNMGGSKKPL NNSNSNIHFL TNQQNSDTPL SNSSSSTPTL
SPAQSAISSP TLSNIINSNS NSTSNLNDLI KDSSQPSTST STSTSSSSSS SSSSSSSSSS
SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS SSSSQPTLNQ HSKYIPKSLH
SSLSSIPINN KENNNNNNNR DNRDKDICTT SPNLNDSINN TLDLFNKKIN SNNNNNNNNS
NNNNNISSQE RPLLNSPHVQ LTHQQQQQQQ QQQQQQQQQH QQQHQKIGMS KSSSELQVPS
SNYHKQSDDL NPLDFLSAIA TMGSNSLSSI LCKDDSKTNT NKDKDNNNSN SNKDSSNNNN
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNINNNEDL LPNPGSSKFA
KYSADQSVSS SSLNTPLSSP IVKSQSYQQP QSQSQQRSQS PLPLHNNISS INTSIHNAIN
SLKPKPLHLS SPSIPTTSPD APYRLPSLNS SSNNINNQSD YWSAINPINS SGTNITNNNY
NNNNNNYNNN NNNNNNNNNN NNNNNNNNNN NNNNNSNSNN NNNNNNNNNN INNNNSNSNN
NMNSNNNNNN INNINNNNNN NNNNNNNNNN NNNNNNNNNN NNNSNSNNNN CNNNNNGGSN
IHSLNNSSNS VNYNNNNNNN NNNINKDKKN KKKLSASTPI FGESNLGDII NNVIDEHQLN
SNNNNNNNTP HFSFNNNSLK ELKPLKRKAS IRNSSGGVIT NENGWTTIVN NNNNNNNNNN
NNNNNNNNNN NNNNNNNNIS SNLPIISGLL SLSKVDSTSV DKL
