ID   Y914_MYCBO              Reviewed;         882 AA.
AC   P59969; A0A1R3XYU0; X2BGB7;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Putative HTH-type transcriptional regulator Mb0914c;
GN   OrderedLocusNames=BQ2027_MB0914C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT708304; SIT99512.1; -; Genomic_DNA.
DR   RefSeq; NP_854571.1; NC_002945.3.
DR   RefSeq; WP_003900227.1; NC_002945.4.
DR   AlphaFoldDB; P59969; -.
DR   SMR; P59969; -.
DR   EnsemblBacteria; SIT99512; SIT99512; BQ2027_MB0914C.
DR   PATRIC; fig|233413.5.peg.995; -.
DR   OMA; RYHWIAG; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..882
FT                   /note="Putative HTH-type transcriptional regulator Mb0914c"
FT                   /id="PRO_0000184200"
FT   DOMAIN          814..879
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        838..857
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   882 AA;  94470 MW;  69415B40F10BD425 CRC64;
     MRALLAQNRL VTLCGTGGVG KTRLAIQIAS ASELRDGLCF VDLAPITESG IVAATAARAV
     GLPDQPGRST MDSLRRFIGN RRMLMVLDNC EHLLDACAAL VVELLGACPE LTILATSREP
     IGMAGEITWR VPSMSITDEA VELFADRASR VQPGFTIANH NAAAVGEICR RLDGIPLAIE
     FAAARVRSMS PLEIADGLDD CFRLLAGGVR GAVQRQQTLR ASIDWSHALL TETEQILFRR
     LAPFVGGFDL AAVRAVAAGS DLDPFSVLDQ LTLLVDKSLV VADDCQGRTR YRLLETVRRY
     ALEKLGDSGE ADVHARHRDY YTALAASLNT PADNDHQRLV ARAETEIDNL RAAFAWSREN
     GHITEALQLA SSLQPIWFGR AHLREGLSWF NSILEDQRFH RLAVSTAVRA RALADKAMLS
     TWLATSPVGA TDIIAPAQQA LAMAREVGDP AALVRALTAC GCSSGYNAEA AAPYFAEATD
     LARAIDDKWT LCQILYWRGV GTCISGDPNA LRAAAEECRD LADTIGDRFV SRHCSLWLSL
     AQMWAGNLTE ALELSREITA EAEASNDVPT KVLGLYTQAQ VLAYCGASAA HAIAGACIAA
     ATELGGVYQG IGYAAMTYAA LAAGDVTAAL EASDAARPIL RAQPDQVTMH QVLMAQLALA
     GGDAIAARQF ANDAVDATNG WHRMVALTIR ARVATARGEP ELARDDAHAA LACGAELHIY
     QGMPDAMELL AGLAGEVGSH SEGVRLLGAA AALRQQTRQV RFKIWDAGYQ ASVTALREAM
     GDEDFDRAWA EGAALSTDEA IAYAQRGRGE RKRPARGWGS LTPTERDVVR LVSEGLSNKD
     IAKRLFVSPR TVQTHLTHVY AKLGLASRVQ LVDEAARRGS PS